Apnea-hypopnea index in nonobese women with polycystic ovary syndrome

Hsiao Ping Yang; Jiunn Horng Kang; Hsiu Yueh Su; Chii Ruey Tzeng; Wei Min Liu; Shih Yi Huang

doi:10.1016/j.ijgo.2009.02.004

Apnea-hypopnea index in nonobese women with polycystic ovary syndrome

Hsiao Ping Yang
, Jiunn Horng Kang
, Hsiu Yueh Su
, Chii Ruey Tzeng
, Wei Min Liu
, Shih Yi Huang

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

Objective: To assess the influence of polycystic ovary syndrome (PCOS) on respiratory events during sleep in nonobese Taiwanese women. Method: Overnight polysomnography was recorded in 18 nonobese women with PCOS who had not received treatment (body mass index [BMI] 21.7 ± 0.57, age 29.1 ± 1.43 years) and in 10 age- and BMI-matched women without PCOS (BMI 20.9 ± 0.58, age 31.6 ± 3.87 years). Results: The nonobese women with PCOS had a higher total apnea-hypopnea index (AHI) especially during the non-rapid eye movement stage (AHI_NREM) than the women who did not have PCOS. The women with PCOS had higher serum levels of high-sensitivity C-reactive protein (hsCRP) and this was positively correlated with AHI_REM. Total testosterone level was positively correlated with AHI_NREM, and androstenedione was negatively correlated with AHI_NREM. Conclusion: PCOS was directly linked to increased obstructive respiratory events during sleep in nonobese women in Taiwan.

Original language	English
Pages (from-to)	226-229
Number of pages	4
Journal	International Journal of Gynecology and Obstetrics
Volume	105
Issue number	3
DOIs	https://doi.org/10.1016/j.ijgo.2009.02.004
Publication status	Published - Jun 2009

Keywords

Androstenedione
Apnea-hypopnea index
Obstructive sleep apnea
Polycystic ovary syndrome
Testosterone

ASJC Scopus subject areas

Obstetrics and Gynaecology

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10.1016/j.ijgo.2009.02.004

Cite this

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title = "Apnea-hypopnea index in nonobese women with polycystic ovary syndrome",

abstract = "Objective: To assess the influence of polycystic ovary syndrome (PCOS) on respiratory events during sleep in nonobese Taiwanese women. Method: Overnight polysomnography was recorded in 18 nonobese women with PCOS who had not received treatment (body mass index [BMI] 21.7 ± 0.57, age 29.1 ± 1.43 years) and in 10 age- and BMI-matched women without PCOS (BMI 20.9 ± 0.58, age 31.6 ± 3.87 years). Results: The nonobese women with PCOS had a higher total apnea-hypopnea index (AHI) especially during the non-rapid eye movement stage (AHINREM) than the women who did not have PCOS. The women with PCOS had higher serum levels of high-sensitivity C-reactive protein (hsCRP) and this was positively correlated with AHIREM. Total testosterone level was positively correlated with AHINREM, and androstenedione was negatively correlated with AHINREM. Conclusion: PCOS was directly linked to increased obstructive respiratory events during sleep in nonobese women in Taiwan.",

keywords = "Androstenedione, Apnea-hypopnea index, Obstructive sleep apnea, Polycystic ovary syndrome, Testosterone",

author = "Yang, \{Hsiao Ping\} and Kang, \{Jiunn Horng\} and Su, \{Hsiu Yueh\} and Tzeng, \{Chii Ruey\} and Liu, \{Wei Min\} and Huang, \{Shih Yi\}",

note = "Funding Information: This work was supported by a grant from Taipei Medical University, Taipei, Taiwan (95TMU-TMUH-09).",

year = "2009",

month = jun,

doi = "10.1016/j.ijgo.2009.02.004",

language = "English",

volume = "105",

pages = "226--229",

journal = "International Journal of Gynecology and Obstetrics",

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publisher = "John Wiley and Sons Ltd",

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AU - Yang, Hsiao Ping

AU - Kang, Jiunn Horng

AU - Su, Hsiu Yueh

AU - Tzeng, Chii Ruey

AU - Liu, Wei Min

AU - Huang, Shih Yi

N1 - Funding Information: This work was supported by a grant from Taipei Medical University, Taipei, Taiwan (95TMU-TMUH-09).

PY - 2009/6

Y1 - 2009/6

N2 - Objective: To assess the influence of polycystic ovary syndrome (PCOS) on respiratory events during sleep in nonobese Taiwanese women. Method: Overnight polysomnography was recorded in 18 nonobese women with PCOS who had not received treatment (body mass index [BMI] 21.7 ± 0.57, age 29.1 ± 1.43 years) and in 10 age- and BMI-matched women without PCOS (BMI 20.9 ± 0.58, age 31.6 ± 3.87 years). Results: The nonobese women with PCOS had a higher total apnea-hypopnea index (AHI) especially during the non-rapid eye movement stage (AHINREM) than the women who did not have PCOS. The women with PCOS had higher serum levels of high-sensitivity C-reactive protein (hsCRP) and this was positively correlated with AHIREM. Total testosterone level was positively correlated with AHINREM, and androstenedione was negatively correlated with AHINREM. Conclusion: PCOS was directly linked to increased obstructive respiratory events during sleep in nonobese women in Taiwan.

AB - Objective: To assess the influence of polycystic ovary syndrome (PCOS) on respiratory events during sleep in nonobese Taiwanese women. Method: Overnight polysomnography was recorded in 18 nonobese women with PCOS who had not received treatment (body mass index [BMI] 21.7 ± 0.57, age 29.1 ± 1.43 years) and in 10 age- and BMI-matched women without PCOS (BMI 20.9 ± 0.58, age 31.6 ± 3.87 years). Results: The nonobese women with PCOS had a higher total apnea-hypopnea index (AHI) especially during the non-rapid eye movement stage (AHINREM) than the women who did not have PCOS. The women with PCOS had higher serum levels of high-sensitivity C-reactive protein (hsCRP) and this was positively correlated with AHIREM. Total testosterone level was positively correlated with AHINREM, and androstenedione was negatively correlated with AHINREM. Conclusion: PCOS was directly linked to increased obstructive respiratory events during sleep in nonobese women in Taiwan.

KW - Androstenedione

KW - Apnea-hypopnea index

KW - Obstructive sleep apnea

KW - Polycystic ovary syndrome

KW - Testosterone

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Apnea-hypopnea index in nonobese women with polycystic ovary syndrome

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Keywords

ASJC Scopus subject areas

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