Antitumor agents. 2. Synthesis and cytotoxic evaluation of 10- bromorutaecarpine

Li Ming Yang; Shwu Jiuan Lin; Lie Chwen Lin; Yao Haur Kuo

Antitumor agents. 2. Synthesis and cytotoxic evaluation of 10- bromorutaecarpine

Li Ming Yang, Shwu Jiuan Lin, Lie Chwen Lin, Yao Haur Kuo

Research output: Contribution to journal › Article › peer-review

Abstract

Derivatives of the quinazolinocarboline alkaloid rutaecarpine, including 10-bromorutaecarpine (1), were synthesized and evaluated for cytotoxicity against several human tumor cell lines. The more potent derivative found in this study was compound 1, which exhibited significant activity against SF- 295 and ovarian cancer cell lines.

Original language	English
Pages (from-to)	219-225
Number of pages	7
Journal	Chinese Pharmaceutical Journal
Volume	51
Issue number	3
Publication status	Published - Jun 1999

Keywords

Antitumor
Evodia rutaecarpa
Quinazolinocarboline alkaloid
Rutaecarpine

ASJC Scopus subject areas

Bioengineering
Pharmaceutical Science

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Antitumor agents. 2. Synthesis and cytotoxic evaluation of 10- bromorutaecarpine",

abstract = "Derivatives of the quinazolinocarboline alkaloid rutaecarpine, including 10-bromorutaecarpine (1), were synthesized and evaluated for cytotoxicity against several human tumor cell lines. The more potent derivative found in this study was compound 1, which exhibited significant activity against SF- 295 and ovarian cancer cell lines.",

keywords = "Antitumor, Evodia rutaecarpa, Quinazolinocarboline alkaloid, Rutaecarpine",

author = "Yang, {Li Ming} and Lin, {Shwu Jiuan} and Lin, {Lie Chwen} and Kuo, {Yao Haur}",

year = "1999",

month = jun,

language = "English",

volume = "51",

pages = "219--225",

journal = "Chinese Pharmaceutical Journal",

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T1 - Antitumor agents. 2. Synthesis and cytotoxic evaluation of 10- bromorutaecarpine

AU - Yang, Li Ming

AU - Lin, Shwu Jiuan

AU - Lin, Lie Chwen

AU - Kuo, Yao Haur

PY - 1999/6

Y1 - 1999/6

N2 - Derivatives of the quinazolinocarboline alkaloid rutaecarpine, including 10-bromorutaecarpine (1), were synthesized and evaluated for cytotoxicity against several human tumor cell lines. The more potent derivative found in this study was compound 1, which exhibited significant activity against SF- 295 and ovarian cancer cell lines.

AB - Derivatives of the quinazolinocarboline alkaloid rutaecarpine, including 10-bromorutaecarpine (1), were synthesized and evaluated for cytotoxicity against several human tumor cell lines. The more potent derivative found in this study was compound 1, which exhibited significant activity against SF- 295 and ovarian cancer cell lines.

KW - Antitumor

KW - Evodia rutaecarpa

KW - Quinazolinocarboline alkaloid

KW - Rutaecarpine

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M3 - Article

AN - SCOPUS:0032768680

SN - 1016-1015

VL - 51

SP - 219

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JO - Chinese Pharmaceutical Journal

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IS - 3

ER -

Antitumor agents. 2. Synthesis and cytotoxic evaluation of 10- bromorutaecarpine

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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