Abstract
The present study was carried out to evaluate the antioxidant activities of bark extract of Acacia confusa and some of the isolated constituents from its ethyl acetate (EtOAc) fraction in various in vitro systems to gain mechanistic insights. Results from antioxidant assays together with authentic antioxidant standards revealed that EtOAc fraction showed strong superoxide radical scavenging activity, reducing power, and ferrous ion-chelating ability. Following an in vitro antioxidant activity-guided fractionation procedure, 16 constituents including 12 benzoic acids, three cinnamic acids and one lignans were isolated and identified from the EtOAc fraction. We also evaluated the structure-activity relationships of benzoic and cinnamic acid derivatives. Results obtained indicated that the bark extracts and the derived phytochemicals from A. confusa have a great potential to prevent disease caused by the overproduction of radicals and also it might be used as a potential source of natural antioxidant agent.
| Original language | English |
|---|---|
| Pages (from-to) | 509-514 |
| Number of pages | 6 |
| Journal | Bioresource Technology |
| Volume | 100 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 2009 |
| Externally published | Yes |
Keywords
- Acacia confusa
- Antioxidant activity
- Free radical
- Phytochemical
- Structure-activity relationships
ASJC Scopus subject areas
- Agronomy and Crop Science
- Food Science
- Process Chemistry and Technology
- Applied Microbiology and Biotechnology