Antihypertensive activity of 6-O-galloyl-D-glucose, a phenolic glycoside from Sapium sebiferum

Feng Lin Hsu; Yung Yung Lee; Juei Tang Cheng

doi:10.1021/np50104a019

Antihypertensive activity of 6-O-galloyl-D-glucose, a phenolic glycoside from Sapium sebiferum

Feng Lin Hsu, Yung Yung Lee, Juei Tang Cheng

Department of Clinical Pharmacy

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

The antihypertensive activity of a phenolic glycoside contained in the leaves of Sapium sebiferum was investigated. From intravenous screening using spontaneously hypertensive rats, 6-O-galloyl-D-glucose was identified as an active substance. The hypotensive action of this compound appears to be produced by an inhibition of noradrenaline release and/or a direct vasodilatation.

Original language	English
Pages (from-to)	308-312
Number of pages	5
Journal	Journal of Natural Products
Volume	57
Issue number	2
DOIs	https://doi.org/10.1021/np50104a019
Publication status	Published - 1994

ASJC Scopus subject areas

Plant Science
Chemistry (miscellaneous)
Drug Discovery
Organic Chemistry
Pharmacology

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title = "Antihypertensive activity of 6-O-galloyl-D-glucose, a phenolic glycoside from Sapium sebiferum",

abstract = "The antihypertensive activity of a phenolic glycoside contained in the leaves of Sapium sebiferum was investigated. From intravenous screening using spontaneously hypertensive rats, 6-O-galloyl-D-glucose was identified as an active substance. The hypotensive action of this compound appears to be produced by an inhibition of noradrenaline release and/or a direct vasodilatation.",

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N2 - The antihypertensive activity of a phenolic glycoside contained in the leaves of Sapium sebiferum was investigated. From intravenous screening using spontaneously hypertensive rats, 6-O-galloyl-D-glucose was identified as an active substance. The hypotensive action of this compound appears to be produced by an inhibition of noradrenaline release and/or a direct vasodilatation.

AB - The antihypertensive activity of a phenolic glycoside contained in the leaves of Sapium sebiferum was investigated. From intravenous screening using spontaneously hypertensive rats, 6-O-galloyl-D-glucose was identified as an active substance. The hypotensive action of this compound appears to be produced by an inhibition of noradrenaline release and/or a direct vasodilatation.

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Antihypertensive activity of 6-O-galloyl-D-glucose, a phenolic glycoside from Sapium sebiferum

Abstract

ASJC Scopus subject areas

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