Anosmia caused by brain tumor

Case Presentation
A 67-year-old health woman presented with a 2-year history of anosmia. The patient went to otolaryngologic clinics for help. Sinuscopic examination of nasal cavity showed no signs of upper respiratory infections, allergic rhinitis, chronic rhinitis, polyps, sinusitis, and nasopharyngeal carcinomas. Nasal airway resistance, evaluated by rhinomanometry, was within normal ranges. Olfactory test revealed total loss of smell. She also denied history of trauma, smoking and overdose of decongestants. Computed tomography of the head showed a huge brain tumor at anterior skull base. Prompt neurosurgery referral was arranged. T1-weighted axial magnetic resonance imaging (with gadolinium) showed a large extra-axial well-enhanced mass lesion measured about 5.9 cm by 5.2 cm along midline of anterior skull base ( Figure A ), with abutting cribriform plate on coronal and sagittal view (arrow in Figure B and Figure C ).