Anesthetic management of a patient with congenital methemoglobinemia

Chiao Y. Lin; Jenn Ming Yang; Chiun Ting Chen; Yung W. Hsu; Chun J. Huang; Chien Chuan Chen; Hsin Jung Tsai

doi:10.1016/S1875-4597(09)60042-4

Anesthetic management of a patient with congenital methemoglobinemia

Chiao Y. Lin, Jenn Ming Yang, Chiun Ting Chen, Yung W. Hsu, Chun J. Huang, Chien Chuan Chen, Hsin Jung Tsai

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Methemoglobinemia occasionally causes cyanosis particularly in congenital methemoglobinemia. Avoidance of exposure to oxidizing agents is important for patients with congenital methemoglobinemia because of their deficient enzymatic pathways and decreased oxygen-carrying capacity. Here, we present a patient with preoperatively undiagnosed congenital methemoglobinemia who underwent uterine myomectomy under general anesthesia. The patient was a 35-year-old woman who displayed a low pulse oximetry reading of 91% prior to induction of anesthesia. Methemoglobinemia was first suspected intraoperatively because of a mismatch of SpO₂ of finger pulse oximetry and SaO₂ of arterial blood, and was later confirmed by multiple-wavelength CO-oximetry. The pathophysiology, etiology, clinical manifestations, anesthetic considerations, and treatment options of methemoglobinemia are discussed.

Original language	English
Pages (from-to)	143-146
Number of pages	4
Journal	Acta Anaesthesiologica Taiwanica
Volume	47
Issue number	3
DOIs	https://doi.org/10.1016/S1875-4597(09)60042-4
Publication status	Published - Sept 2009
Externally published	Yes

Keywords

Methemoglobinemia: congenital
Oxygen: saturation

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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10.1016/S1875-4597(09)60042-4

Cite this

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abstract = "Methemoglobinemia occasionally causes cyanosis particularly in congenital methemoglobinemia. Avoidance of exposure to oxidizing agents is important for patients with congenital methemoglobinemia because of their deficient enzymatic pathways and decreased oxygen-carrying capacity. Here, we present a patient with preoperatively undiagnosed congenital methemoglobinemia who underwent uterine myomectomy under general anesthesia. The patient was a 35-year-old woman who displayed a low pulse oximetry reading of 91% prior to induction of anesthesia. Methemoglobinemia was first suspected intraoperatively because of a mismatch of SpO2 of finger pulse oximetry and SaO2 of arterial blood, and was later confirmed by multiple-wavelength CO-oximetry. The pathophysiology, etiology, clinical manifestations, anesthetic considerations, and treatment options of methemoglobinemia are discussed.",

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AU - Lin, Chiao Y.

AU - Yang, Jenn Ming

AU - Chen, Chiun Ting

AU - Hsu, Yung W.

AU - Huang, Chun J.

AU - Chen, Chien Chuan

AU - Tsai, Hsin Jung

PY - 2009/9

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N2 - Methemoglobinemia occasionally causes cyanosis particularly in congenital methemoglobinemia. Avoidance of exposure to oxidizing agents is important for patients with congenital methemoglobinemia because of their deficient enzymatic pathways and decreased oxygen-carrying capacity. Here, we present a patient with preoperatively undiagnosed congenital methemoglobinemia who underwent uterine myomectomy under general anesthesia. The patient was a 35-year-old woman who displayed a low pulse oximetry reading of 91% prior to induction of anesthesia. Methemoglobinemia was first suspected intraoperatively because of a mismatch of SpO2 of finger pulse oximetry and SaO2 of arterial blood, and was later confirmed by multiple-wavelength CO-oximetry. The pathophysiology, etiology, clinical manifestations, anesthetic considerations, and treatment options of methemoglobinemia are discussed.

AB - Methemoglobinemia occasionally causes cyanosis particularly in congenital methemoglobinemia. Avoidance of exposure to oxidizing agents is important for patients with congenital methemoglobinemia because of their deficient enzymatic pathways and decreased oxygen-carrying capacity. Here, we present a patient with preoperatively undiagnosed congenital methemoglobinemia who underwent uterine myomectomy under general anesthesia. The patient was a 35-year-old woman who displayed a low pulse oximetry reading of 91% prior to induction of anesthesia. Methemoglobinemia was first suspected intraoperatively because of a mismatch of SpO2 of finger pulse oximetry and SaO2 of arterial blood, and was later confirmed by multiple-wavelength CO-oximetry. The pathophysiology, etiology, clinical manifestations, anesthetic considerations, and treatment options of methemoglobinemia are discussed.

KW - Methemoglobinemia: congenital

KW - Oxygen: saturation

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ER -

Anesthetic management of a patient with congenital methemoglobinemia

Abstract

Keywords

ASJC Scopus subject areas

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