Abstract
Discovering the interactions between proteins mentioned in biomedical literature is one of the core topics of text mining in the life sciences. In this paper, we propose an interaction pattern generation approach to capture frequent PPI patterns in text. We also present an interaction pattern tree kernel method that integrates the PPI pattern with convolution tree kernel to extract protein-protein interactions. Empirical evaluations on LLL, IEPA, and HPRD50 corpora demonstrate that our method is effective and outperforms several wellknown PPI extraction methods.
Original language | English |
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Pages (from-to) | 36-46 |
Number of pages | 11 |
Journal | Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) |
Volume | 8916 |
DOIs | |
Publication status | Published - 2014 |
Externally published | Yes |
Keywords
- Interaction pattern generation
- Interaction pattern tree kernel
- Protein-protein interaction
- Text mining
ASJC Scopus subject areas
- Theoretical Computer Science
- General Computer Science