An integrated microfluidic chip for the study of metastasis and angiogenesis

Yong Yu Hsu; Kuo Wei Chang; Tse Shao Chen; Kang Yun Lee; Chen Shien Liu

doi:10.1109/NEMS.2014.6908842

An integrated microfluidic chip for the study of metastasis and angiogenesis

Yong Yu Hsu, Kuo Wei Chang, Tse Shao Chen, Kang Yun Lee, Chen Shien Liu

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

Abstract

Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.

Original language	English
Title of host publication	9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	426-429
Number of pages	4
ISBN (Print)	9781479947270
DOIs	https://doi.org/10.1109/NEMS.2014.6908842
Publication status	Published - Sept 23 2014
Event	9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014 - Waikiki Beach, United States Duration: Apr 13 2014 → Apr 16 2014

Other

Other	9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014
Country/Territory	United States
City	Waikiki Beach
Period	4/13/14 → 4/16/14

Keywords

angiogenesis
extracellular matrix (ECM)
Lung cancer
pattern
vascular endothelial cell

ASJC Scopus subject areas

Control and Systems Engineering
Electrical and Electronic Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1109/NEMS.2014.6908842

Cite this

Hsu, Y. Y., Chang, K. W., Chen, T. S., Lee, K. Y., & Liu, C. S. (2014). An integrated microfluidic chip for the study of metastasis and angiogenesis. In 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014 (pp. 426-429). [6908842] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NEMS.2014.6908842

An integrated microfluidic chip for the study of metastasis and angiogenesis. / Hsu, Yong Yu; Chang, Kuo Wei; Chen, Tse Shao et al.
9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014. Institute of Electrical and Electronics Engineers Inc., 2014. p. 426-429 6908842.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Hsu, YY, Chang, KW, Chen, TS, Lee, KY & Liu, CS 2014, An integrated microfluidic chip for the study of metastasis and angiogenesis. in 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014., 6908842, Institute of Electrical and Electronics Engineers Inc., pp. 426-429, 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014, Waikiki Beach, United States, 4/13/14. https://doi.org/10.1109/NEMS.2014.6908842

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AB - Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.

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An integrated microfluidic chip for the study of metastasis and angiogenesis

Abstract

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Keywords

ASJC Scopus subject areas

UN SDGs

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