TY - GEN
T1 - An integrated microfluidic chip for the study of metastasis and angiogenesis
AU - Hsu, Yong Yu
AU - Chang, Kuo Wei
AU - Chen, Tse Shao
AU - Lee, Kang Yun
AU - Liu, Chen Shien
N1 - Publisher Copyright:
© 2014 IEEE.
PY - 2014/9/23
Y1 - 2014/9/23
N2 - Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.
AB - Cancer is a seriously disease in the modern, and lung cancer is one of the cancers with the high fatality rate. There are some clinical strategies to cure cancer, like surgery, radiation and chemotherapy. Even we have many solutions to treat with cancer, but they are still with some shortages. According to the literature survey and clinical experts, the ability of a tumor to achieve vascularization is an essential hallmark of cancer biology. Recently, cell based systems has become the target to develop new cancer therapy for the inhibition of tumor angiogenesis. In this research, we demonstrated a platform which is based on the concentration gradient generator and DEP cell pattern technology, to study the relationship between angiogenesis and tumor cell.
KW - Lung cancer
KW - angiogenesis
KW - extracellular matrix (ECM)
KW - pattern
KW - vascular endothelial cell
UR - http://www.scopus.com/inward/record.url?scp=84908619545&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84908619545&partnerID=8YFLogxK
U2 - 10.1109/NEMS.2014.6908842
DO - 10.1109/NEMS.2014.6908842
M3 - Conference contribution
AN - SCOPUS:84908619545
T3 - 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014
SP - 426
EP - 429
BT - 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 9th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, IEEE-NEMS 2014
Y2 - 13 April 2014 through 16 April 2014
ER -
