An expedited model for identifying potential patients with periodic leg movements

Po-Yueh Chen, Shang-Yang Lin, Chung-Sheng Wu, Shih-Han Hung, David Hsin-Kuang Chen, Wen-Te Liu, Yi-Chih Lin

Research output: Contribution to journalArticlepeer-review


Periodic leg movements during sleep (PLMS) may have crucial consequences in adults. This study aimed to identify baseline characteristics, symptoms, or questionnaires that could help to identify sleep-disordered breathing patients with significant PLMS. Patients aged 20-80 years who underwent polysomnography for assessing sleep disturbance were included. Various factors such as sex, age, body measurements, symptoms, apnea-hypopnea index (AHI), and sleep quality scales were analysed to determine the presence of PLMS. The study included 1480 patients with a mean age of 46.4 ± 13.4 years, among whom 110 (7.4%) had significant PLMS with a PLM index of 15 or higher. There were no significant differences observed in terms of sex or BMI between patients with and without significant PLMS. However, the odds ratios (OR) for PLMS were 4.33, 4.41, and 4.23 in patients who were aged over 50 years, had insomnia, or had an ESS score of less than 10, respectively. Notably, the OR increased up to 67.89 times in patients who presented with all three risk factors. Our analysis identified significant risk factors for PLMS: age over 50, self-reported insomnia, and lower daytime sleepiness levels. These findings aid in identifying potential PLMS patients, facilitating confirmatory examinations and managing associated comorbidities.

Original languageEnglish
Pages (from-to)e14198
JournalJournal of Sleep Research
Publication statusE-pub ahead of print - Mar 18 2024


Dive into the research topics of 'An expedited model for identifying potential patients with periodic leg movements'. Together they form a unique fingerprint.

Cite this