An acute psychiatric episode following transvaginal oocyte retrieval

Jiann Loung Hwang, Min Che Kuo, Bih Chwen Hsieh, Chien Hui Chang, Lih Chih Jou, Wei Hung Chen, Gong Jhe Wu

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Psychological disorders of infertile patients are traditionally thought to be chronic, to advance gradually, and to be long-term problems. We describe a patient in whom an acute psychiatric episode developed immediately after transvaginal ultrasound-guided oocyte retrieval. A 34 year old women without history of psychiatric disturbance or adverse reaction to drugs suffered an acute psychiatric episode immediately after oocyte retrieval. She exhibited tachycardia, tachypnoea, transient hypertension and limb rigidity, as well as alterations to stupor and posture. Her vital signs stabilized and she opened her eyes 6 h later, but she persistently raised her head to the left and stared blankly without response to external stimuli. Nine hours later, she was able to look around but remained unresponsive to stimuli. Aphasia was noted in the next morning and a wishful thinking of having delivered a baby was noted in the afternoon. Memory loss was noted on the third day. The patient was diagnosed as having dissociative amnesia and was discharged after three courses of supportive psychotherapy. Assisted reproductive technology-related acute psychiatric episodes, which may initially mimic brainstem stroke, are rare; however, attention should be paid to high-risk patients, and they should be offered elective psychological counselling.

Original languageEnglish
Pages (from-to)1124-1126
Number of pages3
JournalHuman Reproduction
Issue number4
Publication statusPublished - 2002
Externally publishedYes


  • Dissociative amnesia
  • Infertility
  • Psychological disorder
  • Stroke
  • Transvaginal ultrasound-guided oocyte retrieval

ASJC Scopus subject areas

  • Physiology
  • Developmental Biology
  • Obstetrics and Gynaecology
  • Reproductive Medicine


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