The association of low-to-moderate arsenic exposure with cause-specific mortality has never been reported in Taiwan. This study aimed to elucidate the dose-response relation of mortality from various causes of death with the arsenic concentration in drinking water and cumulative arsenic exposure. A total of 8,088 residents from northeastern Taiwan were followed from 1991 to 2011. Cox regression analysis was used to determine the hazard ratio of cause-specific mortality associated with two indices of arsenic exposure. A total of 3,106 deaths were ascertained during the follow-up period of 120,768 person-years. The multivariate-adjusted hazard ratio (95% confidence interval) was 1.25 (1.04-1.50), 1.32 (0.96-1.81), 2.41 (1.43-4.05), 4.00 (1.17-13.70), 3.58 (0.92-13.93) and 2.31 (1.43-3.75), respectively, for mortality from all-causes, all cancers, lung cancer, urinary cancer, occlusive stroke, and respiratory disease for arsenic level in drinking water ≥500.0 μg/L compared to

Original languageEnglish
Title of host publicationOne Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment
PublisherCRC Press/Balkema
Number of pages2
ISBN (Print)9781138001411
Publication statusPublished - 2014
Event5th International Congress on Arsenic in the Environment, As 2014 - Buenos Aires, Argentina
Duration: May 11 2014May 16 2014


Other5th International Congress on Arsenic in the Environment, As 2014
CityBuenos Aires

ASJC Scopus subject areas

  • Chemical Health and Safety


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