All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan

B. Y. Hsiao; L. I. Hsu; C. J. Chen; Hung Yi Chiou

All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan

B. Y. Hsiao, L. I. Hsu, C. J. Chen, Hung Yi Chiou

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The association of low-to-moderate arsenic exposure with cause-specific mortality has never been reported in Taiwan. This study aimed to elucidate the dose-response relation of mortality from various causes of death with the arsenic concentration in drinking water and cumulative arsenic exposure. A total of 8,088 residents from northeastern Taiwan were followed from 1991 to 2011. Cox regression analysis was used to determine the hazard ratio of cause-specific mortality associated with two indices of arsenic exposure. A total of 3,106 deaths were ascertained during the follow-up period of 120,768 person-years. The multivariate-adjusted hazard ratio (95% confidence interval) was 1.25 (1.04-1.50), 1.32 (0.96-1.81), 2.41 (1.43-4.05), 4.00 (1.17-13.70), 3.58 (0.92-13.93) and 2.31 (1.43-3.75), respectively, for mortality from all-causes, all cancers, lung cancer, urinary cancer, occlusive stroke, and respiratory disease for arsenic level in drinking water ≥500.0 μg/L compared to

Original language	English
Title of host publication	One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment
Publisher	CRC Press/Balkema
Pages	580-581
Number of pages	2
ISBN (Print)	9781138001411
Publication status	Published - 2014
Event	5th International Congress on Arsenic in the Environment, As 2014 - Buenos Aires, Argentina Duration: May 11 2014 → May 16 2014

Other

Other	5th International Congress on Arsenic in the Environment, As 2014
Country/Territory	Argentina
City	Buenos Aires
Period	5/11/14 → 5/16/14

ASJC Scopus subject areas

Chemical Health and Safety

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

Hsiao, B. Y., Hsu, L. I., Chen, C. J., & Chiou, H. Y. (2014). All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan. In One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment (pp. 580-581). CRC Press/Balkema.

All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan. / Hsiao, B. Y.; Hsu, L. I.; Chen, C. J. et al.
One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. CRC Press/Balkema, 2014. p. 580-581.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Hsiao, BY, Hsu, LI, Chen, CJ & Chiou, HY 2014, All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan. in One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. CRC Press/Balkema, pp. 580-581, 5th International Congress on Arsenic in the Environment, As 2014, Buenos Aires, Argentina, 5/11/14.

Hsiao BY, Hsu LI, Chen CJ, Chiou HY. All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan. In One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. CRC Press/Balkema. 2014. p. 580-581

Hsiao, B. Y. ; Hsu, L. I. ; Chen, C. J. et al. / All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water : A prospective cohort study in northeastern Taiwan. One Century of the Discovery of Arsenicosis in Latin America (1914-2014): As 2014 - Proceedings of the 5th International Congress on Arsenic in the Environment. CRC Press/Balkema, 2014. pp. 580-581

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abstract = "The association of low-to-moderate arsenic exposure with cause-specific mortality has never been reported in Taiwan. This study aimed to elucidate the dose-response relation of mortality from various causes of death with the arsenic concentration in drinking water and cumulative arsenic exposure. A total of 8,088 residents from northeastern Taiwan were followed from 1991 to 2011. Cox regression analysis was used to determine the hazard ratio of cause-specific mortality associated with two indices of arsenic exposure. A total of 3,106 deaths were ascertained during the follow-up period of 120,768 person-years. The multivariate-adjusted hazard ratio (95% confidence interval) was 1.25 (1.04-1.50), 1.32 (0.96-1.81), 2.41 (1.43-4.05), 4.00 (1.17-13.70), 3.58 (0.92-13.93) and 2.31 (1.43-3.75), respectively, for mortality from all-causes, all cancers, lung cancer, urinary cancer, occlusive stroke, and respiratory disease for arsenic level in drinking water ≥500.0 μg/L compared to ",

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AB - The association of low-to-moderate arsenic exposure with cause-specific mortality has never been reported in Taiwan. This study aimed to elucidate the dose-response relation of mortality from various causes of death with the arsenic concentration in drinking water and cumulative arsenic exposure. A total of 8,088 residents from northeastern Taiwan were followed from 1991 to 2011. Cox regression analysis was used to determine the hazard ratio of cause-specific mortality associated with two indices of arsenic exposure. A total of 3,106 deaths were ascertained during the follow-up period of 120,768 person-years. The multivariate-adjusted hazard ratio (95% confidence interval) was 1.25 (1.04-1.50), 1.32 (0.96-1.81), 2.41 (1.43-4.05), 4.00 (1.17-13.70), 3.58 (0.92-13.93) and 2.31 (1.43-3.75), respectively, for mortality from all-causes, all cancers, lung cancer, urinary cancer, occlusive stroke, and respiratory disease for arsenic level in drinking water ≥500.0 μg/L compared to

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AN - SCOPUS:84907340004

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ER -

All-cause and cause-specific mortality and long-term exposure to arsenic in drinking water: A prospective cohort study in northeastern Taiwan

Abstract

Other

ASJC Scopus subject areas

UN SDGs

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