TY - JOUR
T1 - Aggressive hepatic resection for patients with pyogenic liver abscess and APACHE II score ≥15
AU - Hsieh, Huan-Fa
AU - Chen, Teng-Wei
AU - Yu, Chih-Yung
AU - Wang, Ning-Chi
AU - Chu, Heng-Cheng
AU - Shih, Ming-Liang
AU - Yu, Jyh-Cherng
AU - Hsieh, Chung-Bao
N1 - 被引用次數：16
Export Date: 22 March 2016
CODEN: AJSUA
通訊地址: Hsieh, C.-B.; Division of General Surgery, Department of Surgery, Tri-Service General Hospital, Taipei, Taiwan; 電子郵件： [email protected]
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PY - 2008
Y1 - 2008
N2 - Background: Most liver abscesses resolve after antimicrobial therapy or percutaneous tube drainage (PD). The aim of this study was to evaluate the results of hepatic resection (HR) for patients with pyogenic liver abscesses and an Acute Physiology and Chronic Health Evaluation II (APACHE II) score ≥15. Methods: We compared the clinical outcomes of 81 patients with APACHE II scores ≥15 undergoing PD and/or HR. Results: The failure rate (3 of 65) and double-treatment rate (32 of 65) in the PD group were significantly higher than in the HR group (3 of 35 vs 0 of 35; P = .0002). The mortality rate in the PD group was significantly higher than the other 2 groups (14 of 46 vs 2 of 19 and 1 of 16; P = .038). The length of hospital stay was significantly shorter and antibiotic use less in the HR group than in the PD group (P <.05). Conclusions: Aggressive HR for patients with liver abscesses and APACHE II scores ≥15 produced better clinical outcomes. © 2008 Elsevier Inc. All rights reserved.
AB - Background: Most liver abscesses resolve after antimicrobial therapy or percutaneous tube drainage (PD). The aim of this study was to evaluate the results of hepatic resection (HR) for patients with pyogenic liver abscesses and an Acute Physiology and Chronic Health Evaluation II (APACHE II) score ≥15. Methods: We compared the clinical outcomes of 81 patients with APACHE II scores ≥15 undergoing PD and/or HR. Results: The failure rate (3 of 65) and double-treatment rate (32 of 65) in the PD group were significantly higher than in the HR group (3 of 35 vs 0 of 35; P = .0002). The mortality rate in the PD group was significantly higher than the other 2 groups (14 of 46 vs 2 of 19 and 1 of 16; P = .038). The length of hospital stay was significantly shorter and antibiotic use less in the HR group than in the PD group (P <.05). Conclusions: Aggressive HR for patients with liver abscesses and APACHE II scores ≥15 produced better clinical outcomes. © 2008 Elsevier Inc. All rights reserved.
KW - APACHE II
KW - Hepatic resection
KW - Pyogenic liver abscess
KW - adult
KW - aged
KW - antibiotic therapy
KW - APACHE
KW - article
KW - female
KW - hospitalization
KW - human
KW - length of stay
KW - liver surgery
KW - major clinical study
KW - male
KW - outcome assessment
KW - priority journal
KW - pyogenic liver abscess
KW - statistical significance
KW - surgical mortality
KW - Aged
KW - Aged, 80 and over
KW - Female
KW - Hepatectomy
KW - Humans
KW - Liver Abscess, Pyogenic
KW - Male
KW - Middle Aged
KW - Treatment Outcome
U2 - 10.1016/j.amjsurg.2007.09.051
DO - 10.1016/j.amjsurg.2007.09.051
M3 - Article
SN - 0002-9610
VL - 196
SP - 346
EP - 350
JO - American Journal of Surgery
JF - American Journal of Surgery
IS - 3
ER -
