TY - JOUR
T1 - Adverse outcomes after non-chest surgeries in patients with pulmonary tuberculosis
T2 - A nationwide study
AU - Ke, Chi Chen
AU - Lin, Chao-Shun
AU - Yeh, Chun Chieh
AU - Chung, Chi-Li
AU - Hung, Chih Jen
AU - Liao, Chien-Chang
AU - Chen, Ta-Liang
AU - Hozbor, Daniela Flavia
N1 - Publisher Copyright:
© 2015 Ke et al.
PY - 2015/7/14
Y1 - 2015/7/14
N2 - Background: The association between pulmonary tuberculosis (TB) and postoperative outcomes remains unknown. This study investigated outcomes following non-chest surgeries in patients with previous pulmonary TB. Methods: Using Taiwan's National Health Insurance Research Database, we analyzed 6911 patients (aged ≥ 20 years) with preoperative diagnosis of pulmonary TB and 6911 propensity scorematched controls receiving non-chest surgeries in 2008-2010. Postoperative outcomes were compared between patients with or without pulmonary TB by calculating adjusted odds ratios (ORs) and 95% confidence intervals (CIs) in the multivariate logistic regressions. Results: Surgical patients with pulmonary TB had a significantly higher postoperative complication rates than controls, including septicemia, pneumonia, acute renal failure, deep wound infection, overall complications, and 30-day postoperative mortality (OR 1.41; 95% CI1.07-1.86). The ORs of patients with low-income status were as high as 2.27 (95% CI1.03-5.03). Preoperative use of TB drugs and TB-related medical expenditure also associated with higher postoperative mortality among surgical patients with pulmonary TB.
AB - Background: The association between pulmonary tuberculosis (TB) and postoperative outcomes remains unknown. This study investigated outcomes following non-chest surgeries in patients with previous pulmonary TB. Methods: Using Taiwan's National Health Insurance Research Database, we analyzed 6911 patients (aged ≥ 20 years) with preoperative diagnosis of pulmonary TB and 6911 propensity scorematched controls receiving non-chest surgeries in 2008-2010. Postoperative outcomes were compared between patients with or without pulmonary TB by calculating adjusted odds ratios (ORs) and 95% confidence intervals (CIs) in the multivariate logistic regressions. Results: Surgical patients with pulmonary TB had a significantly higher postoperative complication rates than controls, including septicemia, pneumonia, acute renal failure, deep wound infection, overall complications, and 30-day postoperative mortality (OR 1.41; 95% CI1.07-1.86). The ORs of patients with low-income status were as high as 2.27 (95% CI1.03-5.03). Preoperative use of TB drugs and TB-related medical expenditure also associated with higher postoperative mortality among surgical patients with pulmonary TB.
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U2 - 10.1371/journal.pone.0133064
DO - 10.1371/journal.pone.0133064
M3 - Article
C2 - 26172153
AN - SCOPUS:84940532101
SN - 1932-6203
VL - 10
JO - PLoS ONE
JF - PLoS ONE
IS - 7
M1 - e0133064
ER -