Adult T-cell leukemia first case reported in Taiwan

P. M. Chen; C. F. Chiu; T. J. Chiou; C. H. Tzeng; B. N. Chiang

Adult T-cell leukemia first case reported in Taiwan

P. M. Chen, C. F. Chiu, T. J. Chiou, C. H. Tzeng, B. N. Chiang

Research output: Contribution to journal › Article › peer-review

Abstract

We examined a 40-year-old male paint worker with migratory joint pain and erythematous-indurated skin lesions over his palms and soles. Hypercalcemia and lymphocytosis with convoluted or indented nuclei were found. The skin biopsy confirmed leukemic infiltration. Skin tests with PHA, PPD and candida extracts were all negative. Surface marker studies of leukemic cells showed OKT3 94%, OKT4 94%, OKT8 4% and OKT9 94%. The serological findings by an indirect fluorescence method with KH-2 cell line were positive in the patient and his wife. Clinically, the patient had a relatively poor response to chemotherapy and died eight months after diagnosis. The entire presented picture was similar to ATL.

Original language	English
Pages (from-to)	1035-1041
Number of pages	7
Journal	Acta Haematologica Japonica
Volume	48
Issue number	4
Publication status	Published - 1985
Externally published	Yes

ASJC Scopus subject areas

Hematology

Cite this

@article{b1af51060a784f3da831c0e0aa46f2f9,

title = "Adult T-cell leukemia first case reported in Taiwan",

abstract = "We examined a 40-year-old male paint worker with migratory joint pain and erythematous-indurated skin lesions over his palms and soles. Hypercalcemia and lymphocytosis with convoluted or indented nuclei were found. The skin biopsy confirmed leukemic infiltration. Skin tests with PHA, PPD and candida extracts were all negative. Surface marker studies of leukemic cells showed OKT3 94%, OKT4 94%, OKT8 4% and OKT9 94%. The serological findings by an indirect fluorescence method with KH-2 cell line were positive in the patient and his wife. Clinically, the patient had a relatively poor response to chemotherapy and died eight months after diagnosis. The entire presented picture was similar to ATL.",

author = "Chen, {P. M.} and Chiu, {C. F.} and Chiou, {T. J.} and Tzeng, {C. H.} and Chiang, {B. N.}",

year = "1985",

language = "English",

volume = "48",

pages = "1035--1041",

journal = "Acta Haematologica Japonica",

issn = "0001-5806",

publisher = "Springer",

number = "4",

}

TY - JOUR

T1 - Adult T-cell leukemia first case reported in Taiwan

AU - Chen, P. M.

AU - Chiu, C. F.

AU - Chiou, T. J.

AU - Tzeng, C. H.

AU - Chiang, B. N.

PY - 1985

Y1 - 1985

N2 - We examined a 40-year-old male paint worker with migratory joint pain and erythematous-indurated skin lesions over his palms and soles. Hypercalcemia and lymphocytosis with convoluted or indented nuclei were found. The skin biopsy confirmed leukemic infiltration. Skin tests with PHA, PPD and candida extracts were all negative. Surface marker studies of leukemic cells showed OKT3 94%, OKT4 94%, OKT8 4% and OKT9 94%. The serological findings by an indirect fluorescence method with KH-2 cell line were positive in the patient and his wife. Clinically, the patient had a relatively poor response to chemotherapy and died eight months after diagnosis. The entire presented picture was similar to ATL.

AB - We examined a 40-year-old male paint worker with migratory joint pain and erythematous-indurated skin lesions over his palms and soles. Hypercalcemia and lymphocytosis with convoluted or indented nuclei were found. The skin biopsy confirmed leukemic infiltration. Skin tests with PHA, PPD and candida extracts were all negative. Surface marker studies of leukemic cells showed OKT3 94%, OKT4 94%, OKT8 4% and OKT9 94%. The serological findings by an indirect fluorescence method with KH-2 cell line were positive in the patient and his wife. Clinically, the patient had a relatively poor response to chemotherapy and died eight months after diagnosis. The entire presented picture was similar to ATL.

UR - http://www.scopus.com/inward/record.url?scp=0021883309&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021883309&partnerID=8YFLogxK

M3 - Article

C2 - 3877390

AN - SCOPUS:0021883309

SN - 0001-5806

VL - 48

SP - 1035

EP - 1041

JO - Acta Haematologica Japonica

JF - Acta Haematologica Japonica

IS - 4

ER -

Adult T-cell leukemia first case reported in Taiwan

Abstract

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this