TY - JOUR
T1 - Adjuvant chemotherapy for resectable gastric cancer
T2 - A preliminary report
AU - Chou, Fong‐Fu ‐F
AU - Sheen‐Chen, Shyr‐Ming ‐M
AU - Liu, Po‐Pen ‐P
AU - Chen, Feng‐Chi ‐C
PY - 1994/12
Y1 - 1994/12
N2 - In this prospectively random study, the effect of oral Ftorafur as an adjuvant chemotherapy was compared with that of oral placebo in patients with Stage II and Stage III gastric cancer. Patients had undergone a subtotal gastrectomy with a resection margin that should have been free of tumors. Ftorafur (10 mg/kg) was given daily to 59 Group A patients. Multiple vitamins were given twice a week to 56 Group B patients. We found that there was no statistical significance in Stage II patients with regard to survival. In Stage III patients, those treated with oral Ftorafur had better ‐3‐year and 5‐year survival rates than those receiving oral placebo. This preliminary report on this ongoing study seems to indicate that long‐term postoperative Ftorafur treatment may be beneficial to Stage III gastric cancer patients. © 1994 Wiley‐Liss, Inc.
AB - In this prospectively random study, the effect of oral Ftorafur as an adjuvant chemotherapy was compared with that of oral placebo in patients with Stage II and Stage III gastric cancer. Patients had undergone a subtotal gastrectomy with a resection margin that should have been free of tumors. Ftorafur (10 mg/kg) was given daily to 59 Group A patients. Multiple vitamins were given twice a week to 56 Group B patients. We found that there was no statistical significance in Stage II patients with regard to survival. In Stage III patients, those treated with oral Ftorafur had better ‐3‐year and 5‐year survival rates than those receiving oral placebo. This preliminary report on this ongoing study seems to indicate that long‐term postoperative Ftorafur treatment may be beneficial to Stage III gastric cancer patients. © 1994 Wiley‐Liss, Inc.
KW - adjuvant chemotherapy
KW - Ftorafur
KW - oral placebo
KW - subtotal gastrectomy
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U2 - 10.1002/jso.2930570407
DO - 10.1002/jso.2930570407
M3 - Article
C2 - 7990479
AN - SCOPUS:0028556390
SN - 0022-4790
VL - 57
SP - 239
EP - 242
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
IS - 4
ER -
