Acquired XO/XY clones in bone marrow of a patient with paroxysmal nocturnal hemoglobinuria (PNH)

J. Whang Peng; T. Knutsen; E. C. Lee; B. Leventhal

doi:10.1182/blood.v47.4.611.bloodjournal474611

Acquired XO/XY clones in bone marrow of a patient with paroxysmal nocturnal hemoglobinuria (PNH)

J. Whang Peng, T. Knutsen, E. C. Lee, B. Leventhal

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Cytogenetic studies showed both 45XO and 46XY clones in the bone marrow of a 76 yr old male with a 17 yr history of paroxysmal nocturnal hemoglobinuria (PNH). ⁵⁵Fe incorporation studies demonstrated that both clones involved the hematopoietic stem cells. The loss of the Y chromosome may reflect an aging phenomenon, rather than be related to the PNH.

Original language	English
Pages (from-to)	611-619
Number of pages	9
Journal	Blood
Volume	47
Issue number	4
DOIs	https://doi.org/10.1182/blood.v47.4.611.bloodjournal474611
Publication status	Published - Dec 1 1976
Externally published	Yes

ASJC Scopus subject areas

Immunology
Biochemistry
Hematology
Cell Biology

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title = "Acquired XO/XY clones in bone marrow of a patient with paroxysmal nocturnal hemoglobinuria (PNH)",

abstract = "Cytogenetic studies showed both 45XO and 46XY clones in the bone marrow of a 76 yr old male with a 17 yr history of paroxysmal nocturnal hemoglobinuria (PNH). 55Fe incorporation studies demonstrated that both clones involved the hematopoietic stem cells. The loss of the Y chromosome may reflect an aging phenomenon, rather than be related to the PNH.",

author = "{Whang Peng}, J. and T. Knutsen and Lee, {E. C.} and B. Leventhal",

year = "1976",

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AU - Whang Peng, J.

AU - Knutsen, T.

AU - Lee, E. C.

AU - Leventhal, B.

PY - 1976/12/1

Y1 - 1976/12/1

N2 - Cytogenetic studies showed both 45XO and 46XY clones in the bone marrow of a 76 yr old male with a 17 yr history of paroxysmal nocturnal hemoglobinuria (PNH). 55Fe incorporation studies demonstrated that both clones involved the hematopoietic stem cells. The loss of the Y chromosome may reflect an aging phenomenon, rather than be related to the PNH.

AB - Cytogenetic studies showed both 45XO and 46XY clones in the bone marrow of a 76 yr old male with a 17 yr history of paroxysmal nocturnal hemoglobinuria (PNH). 55Fe incorporation studies demonstrated that both clones involved the hematopoietic stem cells. The loss of the Y chromosome may reflect an aging phenomenon, rather than be related to the PNH.

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Acquired XO/XY clones in bone marrow of a patient with paroxysmal nocturnal hemoglobinuria (PNH)

Abstract

ASJC Scopus subject areas

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