Abdominal auras in patients with mesial temporal sclerosis

Yi-Chun Kuan, Yang Hsin Shih, Chien Chen, Hsiang Yu Yu, Chun Hing Yiu, Yung Yang Lin, Shang Yeong Kwan, Der Jen Yen

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


To better clarify abdominal auras and their clinical correlates, we enrolled 331 temporal lobe epilepsy patients who received surgical treatment. Detailed descriptions of their auras were obtained before surgery and reconfirmed during postoperative outpatient follow-ups. Pathology revealed mesial temporal sclerosis (MTS) in 256 patients (77.3%) and 75 non-MTS. Of 214 MTS patients with auras, 78 (36.4%) reported abdominal auras (vs. 30.4% in non-MTS, p=0.439): 42 with left-sided seizure onset, and 36 with right-sided seizure onset. Moreover, 49 of the 78 MTS patients had abdominal auras accompanied by rising sensations (vs. 2 of 14 in non-MTS group, p=0.004). The "rising air" was initially described to locate to the epigastric (47.8%) or periumbilical area (45.7%) and mostly reached the chest (40.4%) or remained in the abdominal region (27.1%). An epigastric location of "rising air" favored a left-sided seizure onset, and non-epigastric areas favored right-sided seizure onset (p=0.018). Finally, we found that abdominal auras with or without rising sensations did not predict postoperative seizure outcomes.

Original languageEnglish
Pages (from-to)386-390
Number of pages5
JournalEpilepsy and Behavior
Issue number3
Publication statusPublished - Nov 2012


  • Abdominal auras
  • Auras
  • Epilepsy surgery
  • Mesial temporal sclerosis
  • Temporal lobe epilepsy

ASJC Scopus subject areas

  • Clinical Neurology
  • Behavioral Neuroscience
  • Neurology


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