A practical approach to reporting treatment abandonment in pediatric chronic conditions

Meaghann S. Weaver; Ramandeep S. Arora; Scott C. Howard; Carmen E. Salaverria; Yen Lin Liu; Raul C. Ribeiro; Catherine G. Lam

doi:10.1002/pbc.25403

A practical approach to reporting treatment abandonment in pediatric chronic conditions

Meaghann S. Weaver, Ramandeep S. Arora, Scott C. Howard, Carmen E. Salaverria, Yen Lin Liu, Raul C. Ribeiro, Catherine G. Lam

Taipei Medical University

Research output: Contribution to journal › Review article › peer-review

28 Citations (Scopus)

Abstract

Treatment abandonment, the failure to complete therapy that is required for definitive disease control, frequently causes treatment failure for pediatric patients in low- and middle-income countries with chronic conditions, particularly cancer. Other forms of incomplete treatment affecting children in all settings, such as nonadherence and loss to follow-up, are often confused with treatment abandonment. Unclear definitions of incomplete treatment dramatically affect reported outcomes. To facilitate disease-specific and cross-sector analyses, we outline a practical approach to categorize forms of incomplete treatment, present distinct semantic categories with case examples and provide an algorithm that could be tailored to disease- and context-specific needs. Pediatr Blood Cancer 2015;62:565-570.

Original language	English
Pages (from-to)	565-570
Number of pages	6
Journal	Pediatric Blood and Cancer
Volume	62
Issue number	4
DOIs	https://doi.org/10.1002/pbc.25403
Publication status	Published - Apr 1 2015

Keywords

Adherence
Chronic disease
Loss to follow-up
Outcome evaluation
Treatment abandonment
Treatment failure

ASJC Scopus subject areas

Oncology
Pediatrics, Perinatology, and Child Health
Hematology
General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/pbc.25403

Cite this

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title = "A practical approach to reporting treatment abandonment in pediatric chronic conditions",

abstract = "Treatment abandonment, the failure to complete therapy that is required for definitive disease control, frequently causes treatment failure for pediatric patients in low- and middle-income countries with chronic conditions, particularly cancer. Other forms of incomplete treatment affecting children in all settings, such as nonadherence and loss to follow-up, are often confused with treatment abandonment. Unclear definitions of incomplete treatment dramatically affect reported outcomes. To facilitate disease-specific and cross-sector analyses, we outline a practical approach to categorize forms of incomplete treatment, present distinct semantic categories with case examples and provide an algorithm that could be tailored to disease- and context-specific needs. Pediatr Blood Cancer 2015;62:565-570.",

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AU - Weaver, Meaghann S.

AU - Arora, Ramandeep S.

AU - Howard, Scott C.

AU - Salaverria, Carmen E.

AU - Liu, Yen Lin

AU - Ribeiro, Raul C.

AU - Lam, Catherine G.

PY - 2015/4/1

Y1 - 2015/4/1

N2 - Treatment abandonment, the failure to complete therapy that is required for definitive disease control, frequently causes treatment failure for pediatric patients in low- and middle-income countries with chronic conditions, particularly cancer. Other forms of incomplete treatment affecting children in all settings, such as nonadherence and loss to follow-up, are often confused with treatment abandonment. Unclear definitions of incomplete treatment dramatically affect reported outcomes. To facilitate disease-specific and cross-sector analyses, we outline a practical approach to categorize forms of incomplete treatment, present distinct semantic categories with case examples and provide an algorithm that could be tailored to disease- and context-specific needs. Pediatr Blood Cancer 2015;62:565-570.

AB - Treatment abandonment, the failure to complete therapy that is required for definitive disease control, frequently causes treatment failure for pediatric patients in low- and middle-income countries with chronic conditions, particularly cancer. Other forms of incomplete treatment affecting children in all settings, such as nonadherence and loss to follow-up, are often confused with treatment abandonment. Unclear definitions of incomplete treatment dramatically affect reported outcomes. To facilitate disease-specific and cross-sector analyses, we outline a practical approach to categorize forms of incomplete treatment, present distinct semantic categories with case examples and provide an algorithm that could be tailored to disease- and context-specific needs. Pediatr Blood Cancer 2015;62:565-570.

KW - Adherence

KW - Chronic disease

KW - Loss to follow-up

KW - Outcome evaluation

KW - Treatment abandonment

KW - Treatment failure

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A practical approach to reporting treatment abandonment in pediatric chronic conditions

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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