A new method for converting nitriles into primary thioamides by sodium trimethylsilanethiolate

P. Y. Lin; W. S. Ku; M. J. Shiao

doi:10.1055/s-1992-26341

A new method for converting nitriles into primary thioamides by sodium trimethylsilanethiolate

P. Y. Lin
, W. S. Ku
, M. J. Shiao

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

A new method was developed for converting nitriles into primary thioamides. Treatment of various nitriles 1 with 1.5-2.5 equivalents of sodium trimethylsilyl sulfide (sodium trimethylsilanethiolate) in 1,3-dimethyl-2-imidazolidinone at 20-35°C for 4-30 hours gave the corresponding thioamides 2 in 27-80% yield.

Original language	English
Pages (from-to)	1219-1220
Number of pages	2
Journal	Synthesis
Issue number	12
DOIs	https://doi.org/10.1055/s-1992-26341
Publication status	Published - 1992
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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title = "A new method for converting nitriles into primary thioamides by sodium trimethylsilanethiolate",

abstract = "A new method was developed for converting nitriles into primary thioamides. Treatment of various nitriles 1 with 1.5-2.5 equivalents of sodium trimethylsilyl sulfide (sodium trimethylsilanethiolate) in 1,3-dimethyl-2-imidazolidinone at 20-35°C for 4-30 hours gave the corresponding thioamides 2 in 27-80\% yield.",

author = "Lin, \{P. Y.\} and Ku, \{W. S.\} and Shiao, \{M. J.\}",

year = "1992",

doi = "10.1055/s-1992-26341",

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journal = "Synthesis",

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publisher = "Georg Thieme Verlag",

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AU - Lin, P. Y.

AU - Ku, W. S.

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Y1 - 1992

N2 - A new method was developed for converting nitriles into primary thioamides. Treatment of various nitriles 1 with 1.5-2.5 equivalents of sodium trimethylsilyl sulfide (sodium trimethylsilanethiolate) in 1,3-dimethyl-2-imidazolidinone at 20-35°C for 4-30 hours gave the corresponding thioamides 2 in 27-80% yield.

AB - A new method was developed for converting nitriles into primary thioamides. Treatment of various nitriles 1 with 1.5-2.5 equivalents of sodium trimethylsilyl sulfide (sodium trimethylsilanethiolate) in 1,3-dimethyl-2-imidazolidinone at 20-35°C for 4-30 hours gave the corresponding thioamides 2 in 27-80% yield.

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UR - https://www.scopus.com/pages/publications/0026677787#tab=citedBy

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DO - 10.1055/s-1992-26341

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JF - Synthesis

IS - 12

ER -

A new method for converting nitriles into primary thioamides by sodium trimethylsilanethiolate

Abstract

ASJC Scopus subject areas

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