A new method for converting nitriles into primary thioamides by sodium trimethylsilanethiolate

P. Y. Lin; W. S. Ku; M. J. Shiao

doi:10.1055/s-1992-26341

A new method for converting nitriles into primary thioamides by sodium trimethylsilanethiolate

P. Y. Lin, W. S. Ku, M. J. Shiao

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

A new method was developed for converting nitriles into primary thioamides. Treatment of various nitriles 1 with 1.5-2.5 equivalents of sodium trimethylsilyl sulfide (sodium trimethylsilanethiolate) in 1,3-dimethyl-2-imidazolidinone at 20-35°C for 4-30 hours gave the corresponding thioamides 2 in 27-80% yield.

Original language	English
Pages (from-to)	1219-1220
Number of pages	2
Journal	Synthesis
Issue number	12
DOIs	https://doi.org/10.1055/s-1992-26341
Publication status	Published - 1992
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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10.1055/s-1992-26341

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abstract = "A new method was developed for converting nitriles into primary thioamides. Treatment of various nitriles 1 with 1.5-2.5 equivalents of sodium trimethylsilyl sulfide (sodium trimethylsilanethiolate) in 1,3-dimethyl-2-imidazolidinone at 20-35°C for 4-30 hours gave the corresponding thioamides 2 in 27-80% yield.",

author = "Lin, {P. Y.} and Ku, {W. S.} and Shiao, {M. J.}",

year = "1992",

doi = "10.1055/s-1992-26341",

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AB - A new method was developed for converting nitriles into primary thioamides. Treatment of various nitriles 1 with 1.5-2.5 equivalents of sodium trimethylsilyl sulfide (sodium trimethylsilanethiolate) in 1,3-dimethyl-2-imidazolidinone at 20-35°C for 4-30 hours gave the corresponding thioamides 2 in 27-80% yield.

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A new method for converting nitriles into primary thioamides by sodium trimethylsilanethiolate

Abstract

ASJC Scopus subject areas

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