@article{637c1321c06d4b46833744ba1fd20762,
title = "A new capnellene skeleton from the octocoral Capnella imbricata (Quoy & Gaimard, 1833)",
abstract = "Chemical investigations on the ethyl acetate extract of the octocoral Capnella imbricata collected from the waters of Taiwan, which led to the isolation of three capnellenes (1–3), including one new metabolite, △9(12)-capnellene-8β,10α,15-triol (1), along with two known metabolites, △9(12)-capnellene-5α,8β,10α-triol (2), and △9(12)-capnellene-8β,10α-diol (3). The structures of the isolated metabolites were elucidated through extensive spectroscopic analyses, while the relative stereochemistry of 3 was confirmed by a single-crystal X-ray diffraction analysis for the first time in this study. Compounds 1–3 were evaluated in terms of their anti-inflammatory activity by examining their inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils.",
keywords = "Anti-inflammatory, Capnella imbricata, Capnellene, Octocoral, X-ray",
author = "Wu, {I. Ting} and Fan, {Yu Chen} and Lin, {Guan Zhou} and Wang, {Yi Lin} and Hwang, {Tsong Long} and Lai, {Kuei Hung} and Chung, {Hsu Ming}",
note = "Funding Information: This research was supported by the grants from the National Pingtung University and the Ministry of Science and Technology, Taiwan (Grant Nos: MOST 110-2320-B-153-001) awarded to Hsu-Ming Chung. The authors are thankful the High Valued Instrument Center, National Sun Yat-sen University, for the mass (MS000600) and NMR (NMR001100) spectra (MOST 110-2731-M-110-001); and to the Instrumentation Center, National Taiwan University for providing X-ray facilities (MOST 110-2731-M-002-001, XRD000200). Funding Information: This research was supported by the grants from the National Pingtung University and the Ministry of Science and Technology, Taiwan (Grant Nos: MOST 110-2320-B-153-001) awarded to Hsu-Ming Chung. The authors are thankful the High Valued Instrument Center, National Sun Yat-sen University, for the mass (MS000600) and NMR (NMR001100) spectra (MOST 110-2731-M-110-001); and to the Instrumentation Center, National Taiwan University for providing X-ray facilities (MOST 110-2731-M-002-001, XRD000200). Publisher Copyright: {\textcopyright} 2022 Elsevier B.V.",
year = "2023",
month = jan,
doi = "10.1016/j.molstruc.2022.133995",
language = "English",
volume = "1271",
journal = "Journal of Molecular Structure",
issn = "0022-2860",
publisher = "Elsevier B.V.",
}