A new γ-lactone from the leaves of Cinnamomum kotoense

Sien Sing Yang, Wen Chi Hou, Li Wei Huang, Zong-Huei Li

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


A new C19 γ-lactone, cinnakotolactone (1), along with a known analogue, isolinderanolide B (2), were isolated from the n-hexane layer of the leaf extracts of Cinnamomum kotoense. Their structures were elucidated on the basis of spectroscopic analysis. The anti-proliferation activities of 1 and 2 were evaluated against human HT29 and MCF-7 cancer cell lines, and their IC50 values ranged from 3.3 ± 0.3 to 25.8 ± 5.3 μM.

Original languageEnglish
Pages (from-to)1246-1250
Number of pages5
JournalNatural Product Research
Issue number13
Publication statusPublished - Nov 2006


  • Anti-proliferation activity
  • Cinnakotolactone
  • Cinnamomum kotoense
  • Lauraceae
  • Leaves

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Plant Science
  • Organic Chemistry


Dive into the research topics of 'A new γ-lactone from the leaves of Cinnamomum kotoense'. Together they form a unique fingerprint.

Cite this