A nationwide survey of fatigue in cancer patients in Taiwan: An unmet need

Kun Ming Rau, Kun Ming Rau, Shiow Ching Shun, Tzeon Jye Chiou, Chang Hsien Lu, Chang Hsien Lu, Wei Hsu Ko, Wei Hsu Ko, Ming Yang Lee, Wen Tsung Huang, Kun Huei Yeh, Cheng Shyong Chang, Cheng Shyong Chang, Ruey Kuen Hsieh

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Background: Cancer-related fatigue (CRF) is an emerging clinical issue, although its prevalence and impact on quality of life (QOL) in cancer patients in Taiwan remain unclear. The present nationwide cross-sectional study was conducted to provide a thorough overview of the prevalence, related factors and impact of CRF in Taiwan. Methods: In this multi-center survey, data were collected using the International Classification of Diseases 10th Revision (ICD-10) Fatigue evaluation, Brief Fatigue Inventory-Taiwan (BFI-T), the Chinese version of the Symptom Distressed Scale and a fatigue experience survey. Logistic regression was used to determine the correlations between fatigue characteristics and the factors studied. Results: A total of 1207 cancer patients were recruited from 23 hospitals in Taiwan. Fatigue was the most distressing symptom in Taiwanese cancer patients. The distress score was higher if CRF was diagnosed using ICD-10 compared with BFI-T. Rest and nutritional supplementation were the most common non-pharmacological treatments; blood transfusion was the most common pharmacological treatment. There were 45% of patients reported not receiving a timely intervention for fatigue. Conclusions: Fatigue is the most bothersome symptom reported by Taiwanese cancer patients. Caregivers should be aware of the impact of CRF on QOL in cancer patients, constantly measure the severity of fatigue and provide appropriate interventions.

Original languageEnglish
Pages (from-to)693-700
Number of pages8
JournalJapanese Journal of Clinical Oncology
Issue number6
Publication statusPublished - May 7 2020


  • cancer
  • fatigue
  • prevalence

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research


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