A mechanistic study on the antibacterial behavior of silver doped bioceramic

Shih Fu Ou; Ren Jei Chung; Li Hsiang Lin; Yi Chen Chiang; Chiung Fang Huang; Keng Liang Ou

doi:10.1016/j.jallcom.2014.12.158

A mechanistic study on the antibacterial behavior of silver doped bioceramic

Shih Fu Ou, Ren Jei Chung, Li Hsiang Lin, Yi Chen Chiang, Chiung Fang Huang, Keng Liang Ou

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Antibacterial bioceramics were successfully fabricated by adding 0.5 wt% silver to yttria-stabilized zirconia (YSZ) and their surface antibacterial properties were investigated. Silver-containing YSZ bioceramics exhibited superior antibacterial rate against both Staphylococcus aureus (99.9%) and Escherichia coli cells (88.6%) compared with non-doped-YSZ. The antibacterial action of silver was seen to proceed through two mechanisms. The released silver ions were demonstrated to destroy bacterial cell walls and membranes. Silver also inhibited the formation of biofilms and prevented bacteria from adhering to the ceramic surface.

Original language	English
Pages (from-to)	362-367
Number of pages	6
Journal	Journal of Alloys and Compounds
Volume	629
DOIs	https://doi.org/10.1016/j.jallcom.2014.12.158
Publication status	Published - Apr 25 2015

Keywords

Bioceramics
Ceramic-metal systems
Yttria stabilized
Zirconia

ASJC Scopus subject areas

Mechanics of Materials
Mechanical Engineering
Metals and Alloys
Materials Chemistry

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10.1016/j.jallcom.2014.12.158

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title = "A mechanistic study on the antibacterial behavior of silver doped bioceramic",

abstract = "Antibacterial bioceramics were successfully fabricated by adding 0.5 wt% silver to yttria-stabilized zirconia (YSZ) and their surface antibacterial properties were investigated. Silver-containing YSZ bioceramics exhibited superior antibacterial rate against both Staphylococcus aureus (99.9%) and Escherichia coli cells (88.6%) compared with non-doped-YSZ. The antibacterial action of silver was seen to proceed through two mechanisms. The released silver ions were demonstrated to destroy bacterial cell walls and membranes. Silver also inhibited the formation of biofilms and prevented bacteria from adhering to the ceramic surface.",

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T1 - A mechanistic study on the antibacterial behavior of silver doped bioceramic

AU - Ou, Shih Fu

AU - Chung, Ren Jei

AU - Lin, Li Hsiang

AU - Chiang, Yi Chen

AU - Huang, Chiung Fang

AU - Ou, Keng Liang

PY - 2015/4/25

Y1 - 2015/4/25

N2 - Antibacterial bioceramics were successfully fabricated by adding 0.5 wt% silver to yttria-stabilized zirconia (YSZ) and their surface antibacterial properties were investigated. Silver-containing YSZ bioceramics exhibited superior antibacterial rate against both Staphylococcus aureus (99.9%) and Escherichia coli cells (88.6%) compared with non-doped-YSZ. The antibacterial action of silver was seen to proceed through two mechanisms. The released silver ions were demonstrated to destroy bacterial cell walls and membranes. Silver also inhibited the formation of biofilms and prevented bacteria from adhering to the ceramic surface.

AB - Antibacterial bioceramics were successfully fabricated by adding 0.5 wt% silver to yttria-stabilized zirconia (YSZ) and their surface antibacterial properties were investigated. Silver-containing YSZ bioceramics exhibited superior antibacterial rate against both Staphylococcus aureus (99.9%) and Escherichia coli cells (88.6%) compared with non-doped-YSZ. The antibacterial action of silver was seen to proceed through two mechanisms. The released silver ions were demonstrated to destroy bacterial cell walls and membranes. Silver also inhibited the formation of biofilms and prevented bacteria from adhering to the ceramic surface.

KW - Bioceramics

KW - Ceramic-metal systems

KW - Yttria stabilized

KW - Zirconia

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JO - Journal of Alloys and Compounds

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ER -

A mechanistic study on the antibacterial behavior of silver doped bioceramic

Abstract

Keywords

ASJC Scopus subject areas

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