A mechanistic study on the antibacterial behavior of silver doped bioceramic

Shih Fu Ou, Ren Jei Chung, Li Hsiang Lin, Yi Chen Chiang, Chiung Fang Huang, Keng Liang Ou

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Antibacterial bioceramics were successfully fabricated by adding 0.5 wt% silver to yttria-stabilized zirconia (YSZ) and their surface antibacterial properties were investigated. Silver-containing YSZ bioceramics exhibited superior antibacterial rate against both Staphylococcus aureus (99.9%) and Escherichia coli cells (88.6%) compared with non-doped-YSZ. The antibacterial action of silver was seen to proceed through two mechanisms. The released silver ions were demonstrated to destroy bacterial cell walls and membranes. Silver also inhibited the formation of biofilms and prevented bacteria from adhering to the ceramic surface.

Original languageEnglish
Pages (from-to)362-367
Number of pages6
JournalJournal of Alloys and Compounds
Publication statusPublished - Apr 25 2015


  • Bioceramics
  • Ceramic-metal systems
  • Yttria stabilized
  • Zirconia

ASJC Scopus subject areas

  • Mechanics of Materials
  • Mechanical Engineering
  • Metals and Alloys
  • Materials Chemistry


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