A large-scale preparation of glaucine was achieved by reacting boldine with trimethylphenylammonium chloride and potassium t-butoxide in high yield. Treatment of glaucine with 30% H202, subsequent with hydrated ferrous sulfate, afforded norglaucine in an overall yield of 40%.
|Number of pages||6|
|Publication status||Published - 2002|
- Large-scale preparation
ASJC Scopus subject areas
- Organic Chemistry