TY - JOUR
T1 - A comparison of Q-switched alexandrite laser and intense pulsed light for the treatment of freckles and lentigines in Asian persons
T2 - A randomized, physician-blinded, split-face comparative trial
AU - Wang, Chia Chen
AU - Sue, Yuh Mou
AU - Yang, Chih Hsiung
AU - Chen, Chih Kang
PY - 2006/5
Y1 - 2006/5
N2 - Background: Q-switched (QS) pigmented lasers and intense pulsed light (IPL) successfully treat pigment disorders. Objective: We sought to compare efficacy and side effects of QS alexandrite laser (QSAL) and IPL for freckle and lentigo treatment in Asians. Methods: In all, 15 patients with freckles and 17 patients with lentigines were treated randomly with one session QSAL in one cheek and two sessions IPL in the other cheek at 4-week intervals. Efficacy was determined using a new pigmentation area and severity index score. Results: All patients experienced improvement (P < .0001). Postinflammatory hyperpigmentation developed in one patient with freckles and 8 patients with lentigines after QSAL. No postinflammatory hyperpigmentation occurred after IPL. Freckles achieved greater improvement after QSAL than IPL (P = .04). In lentigines, the results after IPL were better than QSAL among those with postinflammatory hyperpigmentation after QSAL. Limitations: Limitations include a small case number and short follow-up period. Conclusion: QSAL was superior to IPL for freckle treatment. IPL should be used for lentigines in Asian persons.
AB - Background: Q-switched (QS) pigmented lasers and intense pulsed light (IPL) successfully treat pigment disorders. Objective: We sought to compare efficacy and side effects of QS alexandrite laser (QSAL) and IPL for freckle and lentigo treatment in Asians. Methods: In all, 15 patients with freckles and 17 patients with lentigines were treated randomly with one session QSAL in one cheek and two sessions IPL in the other cheek at 4-week intervals. Efficacy was determined using a new pigmentation area and severity index score. Results: All patients experienced improvement (P < .0001). Postinflammatory hyperpigmentation developed in one patient with freckles and 8 patients with lentigines after QSAL. No postinflammatory hyperpigmentation occurred after IPL. Freckles achieved greater improvement after QSAL than IPL (P = .04). In lentigines, the results after IPL were better than QSAL among those with postinflammatory hyperpigmentation after QSAL. Limitations: Limitations include a small case number and short follow-up period. Conclusion: QSAL was superior to IPL for freckle treatment. IPL should be used for lentigines in Asian persons.
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U2 - 10.1016/j.jaad.2006.01.012
DO - 10.1016/j.jaad.2006.01.012
M3 - Article
C2 - 16635661
AN - SCOPUS:33646110284
SN - 0190-9622
VL - 54
SP - 804
EP - 810
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 5
ER -