A Case Report of Microcystic Adnesal Carcinoma Treated with Mohs Micrographic Surgery

Microcystic adnexal carcinoma is a rare cutaneous appendageal malignancy, which is characterized by local aggressiveness. Histopathologically and immuno-histopathologically, the tumor reveals mixed eccrine and pilar differentiation. To date, Mohs micrographic surgery providcs a more effective therapy and better outcome than traditional wide excision. We report a 66-year-old male with a slowly growing whitish indurated plaque approaching his left nasolabial area for at least 20 years. A diagnostic biopsy showed deeply infiltrating cords and strands of tumor cells with eccrine-like and pilar-like differentiation surrounded by a sclerotic stroma. Microcystic adenxal carcinoma was diagnosed and Mohs micrographic surgery was performed consequently. This is the first reported case treated with Mohs micrographic surgery in Taiwan.