Japanese encephalitis virus (JEV) infection can manifest with nonspecific febrile illness, aseptic meningitis or encephalitis with or without neurological deficits. JEV typically attacks the thalamus, corpus striatum, brainstem and spinal cord. The laboratory diagnosis of JEV infection involves the detection of anti-JEV antibody IgMs using an enzyme-linked immunosorbent assay (ELISA), which has high sensitivity and specificity. Because of the lack of a specific antiviral therapy, JE is usually managed by symptomatic treatment and supportive care. We report a case of JE in a 34-year-old man. With a clinical presentation similar to herpes simplex virus encephalitis, the patient was finally diagnosed as having JE. The distinction of different viral encephalitides in MR findings is briefly reviewed.

Original languageEnglish
Pages (from-to)134-137
Number of pages4
JournalActa Neurologica Taiwanica
Issue number4
Publication statusPublished - 2014


  • Herpes simplex virus
  • Japanese encephalitis virus
  • Viral encephalitis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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