TY - JOUR
T1 - A 2-year follow-up of swallowing function after radiation therapy in patients with nasopharyngeal carcinoma
AU - Chang, Yeun Chung
AU - Chen, Ssu Yuan
AU - Ting, Lai Lei
AU - Peng, Steven Sin Fong
AU - Wang, Teh Chen
AU - Wang, Tyng Guey
PY - 2011/11/1
Y1 - 2011/11/1
N2 - Objective: To evaluate over a 2-year period the serial swallowing function of patients with nasopharyngeal carcinoma (NPC) after completing radiotherapy (RT). Design: Prospective longitudinal follow-up. Setting: University hospital. Participants: Patients with NPC (N=76) referred for RT: 53 of them at 1 year after RT, and 23 at 2 years after RT. Interventions: Not applicable. Main Outcome Measures: Participants completed a questionnaire and had a video-recorded fluoroscopic swallowing study before RT and 1 month, 1 year, and 2 years after RT. Results: The highest incidence of dysphagia symptoms and retropharyngeal soft tissue swelling occurred in the first month after RT and decreased over time. Pharyngeal transit time was prolonged continuously up to 1 year after RT. Epiglottic vallecular stasis and pharyngeal mucosal coating were worst in the first month after RT and stable afterwards. Aspiration was uncommon during the first 2 years after RT. Conclusions: At a 2-year follow-up after RT, patients with NPC had a progressively increasing pharyngeal transit time, although the subjectively identified symptoms of dysphagia decreased after the first month after RT.
AB - Objective: To evaluate over a 2-year period the serial swallowing function of patients with nasopharyngeal carcinoma (NPC) after completing radiotherapy (RT). Design: Prospective longitudinal follow-up. Setting: University hospital. Participants: Patients with NPC (N=76) referred for RT: 53 of them at 1 year after RT, and 23 at 2 years after RT. Interventions: Not applicable. Main Outcome Measures: Participants completed a questionnaire and had a video-recorded fluoroscopic swallowing study before RT and 1 month, 1 year, and 2 years after RT. Results: The highest incidence of dysphagia symptoms and retropharyngeal soft tissue swelling occurred in the first month after RT and decreased over time. Pharyngeal transit time was prolonged continuously up to 1 year after RT. Epiglottic vallecular stasis and pharyngeal mucosal coating were worst in the first month after RT and stable afterwards. Aspiration was uncommon during the first 2 years after RT. Conclusions: At a 2-year follow-up after RT, patients with NPC had a progressively increasing pharyngeal transit time, although the subjectively identified symptoms of dysphagia decreased after the first month after RT.
KW - Deglutition disorders
KW - Nasopharyngeal neoplasma carcinoma
KW - Radiation
KW - Rehabilitation
UR - http://www.scopus.com/inward/record.url?scp=80054995029&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80054995029&partnerID=8YFLogxK
U2 - 10.1016/j.apmr.2011.06.008
DO - 10.1016/j.apmr.2011.06.008
M3 - Article
C2 - 21840500
AN - SCOPUS:80054995029
SN - 0003-9993
VL - 92
SP - 1814
EP - 1819
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
IS - 11
ER -