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• Thermosenstive injectable hydrogel for drug delivery

  Jhan, H. J. (Inventor), Ho, H.-O. (Inventor), Sheu, M.-T. (Inventor), Shen, S.-C. (Inventor), Ho, Y.-S. (Inventor) & Liu, J.-J. (Inventor), Jun 14 2016, Patent No. US 9,364,545 B2 , Jun 19 2014, Priority date Jun 19 2014

  Research output: Patent

  4 Downloads (Pure)

• The atypical mammalian ligand Delta-like homologue 1 (Dlk1) can regulate Notch signalling in Drosophila

  Bray, S. J., Takada, S., Harrison, E., Shen, S. C. & Ferguson-Smith, A. C., 2008, In: BMC Developmental Biology. 8, 11.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  79 Citations (Scopus)

• Bcl-2 prevents topoisomerase II inhibitor GL331-induced apoptosis is mediated by down-regulation of poly(ADP-ribose)polymerase activity

  Kuo, M. L., Shen, S. C., Yang, C. H., Chuang, S. E., Cheng, A. L. & Huang, T. S., Oct 29 1998, In: Oncogene. 17, 17, p. 2225-2234 10 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Influence of nicotinamide on the development of Propionibacterium acnes biofilm: A preliminary study

  Shih, Y.-H., Lee, W.-R., Lee, M.-J. & Shen, S.-C., 2015, In: Journal of the American Academy of Dermatology. 72, 5, Supplement 1, p. AB8

  Research output: Contribution to journal › Article › peer-review

• Taxol-induced p34(cdc2) kinase activation and apoptosis inhibited by 12- O-Tetradecanoylphorbol-13-acetate in human breast MCF-7 carcinoma cells

  Shen, S. C., Huang, T. S., Jee, S. H. & Kuo, M. L., 1998, In: Cell Growth and Differentiation. 9, 1, p. 23-29 7 p.

  Research output: Contribution to journal › Article › peer-review
  96 Citations (Scopus)

• Transdermal drug delivery enhanced and controlled by erbium:YAG laser: A comparative study of lipophilic and hydrophilic drugs

  Lee, W. R., Shen, S. C., Lai, H. H., Hu, C.-H. & Fang, J. Y., Jul 10 2001, In: Journal of Controlled Release. 75, 1-2, p. 155-166 12 p.

  Research output: Contribution to journal › Article › peer-review
  106 Citations (Scopus)

• Cellular apoptosis susceptibility (CSE1L/CAS) protein in cancer metastasis and chemotherapeutic drug-induced apoptosis

  Tai, C.-J., Hsu, C.-H., Shen, S.-C., Lee, W.-R. & Jiang, M. C., 2010, In: Journal of Experimental and Clinical Cancer Research. 29, 1, 110.

  Research output: Contribution to journal › Review article › peer-review

  Open Access
  49 Citations (Scopus)

• Presence of CSE1L protein in urine of patients with urinary bladder urothelial carcinomas

  Tai, C. J., Liao, C. F., Su, T. C., Shen, K. H., Chang, C. C., Lin, S. H., Yeh, C. M., Shen, S. C., Lee, W. R., Chiou, J. F., Lin, C. H., Chen, Y. C., Shih, H. Y., Yeh, K. T. & Jiang, M. C., Jul 2012, In: International Journal of Biological Markers. 27, 3, p. e280-e284

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• The effect of laser treatment on skin to enhance and control transdermal delivery of 5-fluorouracil

  Lee, W. R., Shen, S. C., Wang, K. H., Hu, J.-H. & Fang, J. Y., 2002, In: Journal of Pharmaceutical Sciences. 91, 7, p. 1613-1626 14 p.

  Research output: Contribution to journal › Article › peer-review
  105 Citations (Scopus)

• Activation of c-Jun NH₂-terminal kinase and subsequent CPP32/Yama during topoisomerase inhibitor β-lapachone-induced apoptosis through an oxidation-dependent pathway

  Shiah, S. G., Chuang, S. E., Chau, Y. P., Shen, S. C. & Kuo, M. L., Jan 16 1999, In: Cancer Research. 59, 2, p. 391-398 8 p.

  Research output: Contribution to journal › Article › peer-review
  95 Citations (Scopus)

• Overexpression of interleukin-6 in human basal cell carcinoma cell lines increases anti-apoptotic activity and tumorigenic potency

  Jee, S. H., Shen, S. C., Chiu, H. C., Tsai, W. L. & Kuo, M. L., Jan 11 2001, In: Oncogene. 20, 2, p. 198-208 11 p.

  Research output: Contribution to journal › Article › peer-review
  122 Citations (Scopus)

• Noninvasive delivery of siRNA and plasmid DNA into skin by fractional ablation: Erbium:YAG laser versus CO₂ laser

  Lee, W.-R., Shen, S.-C., Chen, W.-Y., Aljuffali, I. A., Suen, S. Y. & Fang, J. Y., Apr 2014, In: European Journal of Pharmaceutics and Biopharmaceutics. 86, 3, p. 315-323 9 p.

  Research output: Contribution to journal › Article › peer-review
  29 Citations (Scopus)

• Skin pretreatment with an Er:YAG laser promotes the transdermal delivery of three narcotic analgesics

  Lee, W. R., Shen, S. C., Fang, C. L., Liu, C. R. & Fang, J. Y., Nov 2007, In: Lasers in Medical Science. 22, 4, p. 271-278 8 p.

  Research output: Contribution to journal › Article › peer-review
  31 Citations (Scopus)

• Effect of liposome encapsulation of tea catechins on their accumulation in basal cell carcinomas

  Fang, J. Y., Lee, W. R., Shen, S. C. & Huang, Y. L., May 2006, In: Journal of Dermatological Science. 42, 2, p. 101-109 9 p.

  Research output: Contribution to journal › Article › peer-review
  117 Citations (Scopus)

• Reactive oxygen species-dependent HSP90 protein cleavage participates in arsenical As^{+ 3}- and MMA^{+ 3}-induced apoptosis through inhibition of telomerase activity via JNK activation

  Shen, S. C., Yang, L. Y., Lin, H. Y., Wu, C. Y., Su, T. H. & Chen, Y. C., Jun 1 2008, In: Toxicology and Applied Pharmacology. 229, 2, p. 239-251 13 p.

  Research output: Contribution to journal › Article › peer-review
  32 Citations (Scopus)

• Nicotine enhancement of lipopolysaccharide/interferon-γ-induced cytotoxicity with elevating nitric oxide production

  Chen, Y. C., Shen, S. C., Lin, H. Y., Tsai, S. H. & Lee, T. J. F., Nov 2 2004, In: Toxicology Letters. 153, 2, p. 191-200 10 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Antidepressants, sertraline and paroxetine, increase calcium influx and induce mitochondrial damage-mediated apoptosis of astrocytes

  Then, C. K., Liu, K. H., Liao, M. H., Chung, K. H., Wang, J. Y. & Shen, S. C., 2017, In: Oncotarget. 8, 70, p. 115490-115502 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  40 Citations (Scopus)

• Flavone inhibition of tumor growth via apoptosis in vitro and in vivo.

  Chen, Y.-C., Shen, S.-C., Chow, J.-M., Ko, C. H. & Tseng, S. W., 2004, In: International Journal of Oncology. 25, 3, p. 661-670 10 p.

  Research output: Contribution to journal › Article › peer-review
  90 Citations (Scopus)

• Correction: Correlations between cytoplasmic CSE1L in neoplastic colorectal glands and depth of tumor penetration and cancer stage (Journal of Translational Medicine, (2013), 11, 1, (29), 10.1186/1479-5876-11-29)

  Tai, C. J., Su, T. C., Jiang, M. C., Chen, H. C., Shen, S. C., Lee, W. R., Liao, C. F., Chen, Y. C., Lin, S. H., Li, L. T., Shen, K. H., Yeh, C. M., Yeh, K. T., Lee, C. H., Shih, H. Y. & Chang, C. C., Dec 2023, In: Journal of Translational Medicine. 21, 1, 315.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• High expression of cytoplasmic phosphorylated CSE1L in malignant melanoma but not in benign nevi: Phosphorylated CSE1L for the discrimination between melanoma and benign nevi

  Chin, S. Y., Wu, P. R., Shih, Y. H., Yeh, C. M., Lee, W. R., Shen, S. C., Yeh, K. T., Jiang, M. C. & Tseng, J. T. P., 2015, In: International Journal of Clinical and Experimental Pathology. 8, 2, p. 1393-1401 9 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Rutinoside at C7 attenuates the apoptosis-inducing activity of flavonoids

  Chen, Y. C., Shen, S. C. & Lin, H. Y., Oct 1 2003, In: Biochemical Pharmacology. 66, 7, p. 1139-1150 12 p.

  Research output: Contribution to journal › Article › peer-review
  97 Citations (Scopus)

• Laser-assisted topical drug delivery by using a low-fluence fractional laser: Imiquimod and macromolecules

  Lee, W. R., Shen, S. C., Al-Suwayeh, S. A., Yang, H. H., Yuan, C. Y. & Fang, J. Y., Aug 10 2011, In: Journal of Controlled Release. 153, 3, p. 240-248 9 p.

  Research output: Contribution to journal › Article › peer-review
  108 Citations (Scopus)

• Erbium: YAG laser resurfacing increases skin permeability and the risk of excessive absorption of antibiotics and sunscreens: The influence of skin recovery on drug absorption

  Lee, W. R., Shen, S. C., Al-Suwayeh, S. A., Li, Y. C. & Fang, J. Y., Jun 1 2012, In: Toxicology Letters. 211, 2, p. 150-158 9 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Cytotoxic effects of metal protoporphyrins in glioblastoma cells: Roles of albumin, reactive oxygen species, and heme oxygenase-1

  Chow, J.-M., Huang, G. C., Lin, H. Y., Shen, S.-C., Yang, L.-Y. & Chen, Y.-C., Mar 15 2008, In: Toxicology Letters. 177, 2, p. 97-107 11 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• HSp90 inhibitors, geldanamycin and radicicol, enhance fisetin-induced cytotoxicity via induction of apoptosis in human colonic cancer cells

  Wu, M. S., Lien, G. S., Shen, S. C., Yang, L. Y. & Chen, Y. C., 2013, In: Evidence-based Complementary and Alternative Medicine. 2013, 987612.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  24 Citations (Scopus)