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  5H-8,9-dimethoxy-5-(2-N,N-dimethylaminoethyl)dibenzo[c,h][1,6] naphthyridin-6-ones and related compounds as TOP1-targeting agents: Influence of structure on the ternary cleavable complex formation

  Kerrigan, J. E., Pilch, D. S., Ruchelman, A. L., Zhou, N., Liu, A., Liu, L. & LaVoie, E. J., Oct 20 2003, In: Bioorganic and Medicinal Chemistry Letters. 13, 20, p. 3395-3399 5 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• 5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: Novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity

  Ruchelman, A. L., Singh, S. K., Ray, A., Wu, X. H., Yang, J. M., Li, T. K., Liu, A., Liu, L. F. & LaVoie, E. J., May 1 2003, In: Bioorganic and Medicinal Chemistry. 11, 9, p. 2061-2073 13 p.

  Research output: Contribution to journal › Article › peer-review
  109 Citations (Scopus)

• 5-HT modulates multiple conductances in immature rat rostral ventrolateral medulla neurones in vitro

  Hwang, L. L. & Dun, N. J., May 15 1999, In: Journal of Physiology. 517, 1, p. 217-228 12 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• 5-Hydroxytryptamine responses in immature rat rostral ventrolateral medulla neurons in vitro

  Hwang, L-L. & Dun, N. J., Sept 1998, In: Journal of Neurophysiology. 80, 3, p. 1033-1041 9 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• 5′CpG island hypermethylation and aberrant transcript splicing both contribute to the inactivation of the FHIT gene in resected non-small cell lung cancer

  Tzao, C., Tsai, H. Y., Chen, J. T., Chen, C. Y. & Wang, Y. C., Sept 2004, In: European Journal of Cancer. 40, 14, p. 2175-2183 9 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• 5-氟尿嘧啶單獨或併用遊離輻射治療人類結腸直腸癌細胞之效果

  Translated title of the contribution: Combined Treatment Effect of 5-Fluorouracil with Ionizing Radiation on Human Colorectal Carcinoma Cells黃正仲, 陳柏元, 鄧文炳, 黃家瑜, 林冠如, 吳國海, 傅秉三 & 林芳仁, 1999, In: 放射治療與腫瘤學. 6, 2, p. 73-82 10 p.

  Research output: Contribution to journal › Article › peer-review

• 6,7-dihydroxy-2-(4′-hydroxyphenyl)naphthalene induces HCT116 cell apoptosis through activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway

  Chiu, C. F., Lai, G. Y., Chen, C. H., Chiu, C. C., Hung, S. W. & Chang, C. F., Jan 1 2019, In: Drug Design, Development and Therapy. 13, p. 1609-1621 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Citations (Scopus)

• ⁶⁰Co contamination in recycled steel resulting in elevated civilian radiation doses: Causes and challenges

  Chang, W. P., Chan, C. C. & Wang, J. D., Sept 1997, In: Health Physics. 73, 3, p. 465-472 8 p.

  Research output: Contribution to journal › Article › peer-review
  27 Citations (Scopus)

• 677TT polymorphism of methelenetetrahydrofolate reductase in combination with low serum vitamin B12 is associated with coronary in-stent restenosis

  Chung, S. L., Chiou, K. R. & Charng, M. J., Mar 1 2006, In: Catheterization and Cardiovascular Interventions. 67, 3, p. 349-355 7 p.

  Research output: Contribution to journal › Article › peer-review

• 6-Acyl-4-aryl/alkyl-5,7-dihydroxycoumarins as anti-inflammatory agents

  Lin, C. M., Huang, S. T., Lee, F. W., Kuo, H-S. & Lin, M. H., Jul 1 2006, In: Bioorganic and Medicinal Chemistry. 14, 13, p. 4402-4409 8 p.

  Research output: Contribution to journal › Article › peer-review
  56 Citations (Scopus)

• 6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to trail-induced apoptosis via reactive oxygen species-mediated increase of dr5

  Chen, C. Y., Tai, C. J., Cheng, J. T., Zheng, J. J., Chen, Y. Z., Liu, T. Z., Yiin, S. J. & Chern, C. L., May 12 2010, In: Journal of Agricultural and Food Chemistry. 58, 9, p. 5604-5611 8 p.

  Research output: Contribution to journal › Article › peer-review
  25 Citations (Scopus)

• 6-Substituted 6H-dibenzo[c,h][2,6]naphthyridin-5-ones: Reversed lactam analogues of ARC-111 with potent topoisomerase I-targeting activity and cytotoxicity

  Zhu, S., Ruchelman, A. L., Zhou, N., Liu, A., Liu, L. F. & LaVoie, E. J., May 1 2006, In: Bioorganic and Medicinal Chemistry. 14, 9, p. 3131-3143 13 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• 7-Acetylsinumaximol b induces apoptosis and autophagy in human gastric carcinoma cells through mitochondria dysfunction and activation of the perk/eif2α/atf4/chop signaling pathway

  Tsai, T. C., Lai, K. H., Su, J. H., Wu, Y. J. & Sheu, J. H., Apr 2018, In: Marine Drugs. 16, 4, 104.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  33 Citations (Scopus)

• 7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents

  Chang, J. Y., Hsieh, H. P., Chang, C. Y., Hsu, K. S., Chiang, Y. F., Chen, C. M., Kuo, C. C. & Liou, J. P., Nov 16 2006, In: Journal of Medicinal Chemistry. 49, 23, p. 6656-6659 4 p.

  Research output: Contribution to journal › Article › peer-review
  54 Citations (Scopus)

• 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel ROCK inhibitor blocks cytoskeleton function and cell migration

  Tsai, C. C., Liu, H. F., Hsu, K. C., Yang, J. M., Chen, C., Liu, K. K., Hsu, T. S. & Chao, J. I., Apr 1 2011, In: Biochemical Pharmacology. 81, 7, p. 856-865 10 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• 7-Ketocholesterol and cholesterol-5α,6α-epoxide induce smooth muscle cell migration and proliferation through the epidermal growth factor receptor/phosphoinositide 3-kinase/Akt signaling pathways

  Liao, P. L., Cheng, Y. W., Li, C. H., Wang, Y. T. & Kang, J. J., Aug 2010, In: Toxicology Letters. 197, 2, p. 88-96 9 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• 8,9-Methylenedioxybenzo[i]phenanthridines: Topoisomerase I-targeting activity and cytotoxicity

  Li, D., Zhao, B., Sim, S. P., Li, T. K., Liu, A., Liu, L. F. & LaVoie, E. J., Aug 15 2003, In: Bioorganic and Medicinal Chemistry. 11, 17, p. 3795-3805 11 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• 836 10-years experience in cystitis glandularis

  Chang, C. H. C., Chen, K-K., Lin, T. L., Pan, C-C., Chang, Y-H., Huang, J., Kuo, J-Y., Chung, H-J. & Lin, T. L., Apr 1 2015, In: European Urology, Supplements. 14, 2, p. e836

  Research output: Contribution to journal › Article › peer-review

• 872 IL-1β is a potential central mediator to Papulopustular Rosacea pathology as determined by paired transcriptomic and proteomic analysis

  Harden, J., Shih, Y., Rajendran, D., Xu, J., Li, R., Hofland, H. & Chang, A. L., 2020, In: Journal of Investigative Dermatology. 140, 7, Supplement, p. S114

  Research output: Contribution to journal › Article › peer-review

• 8‐hydroxydaidzein, an isoflavone from fermented soybean, induces autophagy, apoptosis, differentiation, and degradation of oncoprotein bcr‐abl in k562 cells

  Wu, P. S., Yen, J. H., Wang, C. Y., Chen, P. Y., Hung, J. H. & Wu, M. J., Nov 2020, In: Biomedicines. 8, 11, p. 1-23 23 p., 506.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Citations (Scopus)

• 8-hydroxydaidzein downregulates JAK/STAT, MMP, oxidative phosphorylation, and PI3K/AKT pathways in K562 cells

  Wu, P. S., Wang, C. Y., Chen, P. S., Hung, J. H., Yen, J. H. & Wu, M. J., Dec 2021, In: Biomedicines. 9, 12, 1907.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  7 Citations (Scopus)

• 981 Alterations of gene expression in papulopustular rosacea by whole transcriptome analysis

  Shih, Y., Xu, J., Kumar, A., Li, R. & Chang, A., 2019, In: Journal of Investigative Dermatology. 139, 5, Supplement, p. S170

  Research output: Contribution to journal › Article › peer-review

• 99mTc pyrene derivative complex causes double-strand breaks in dsDNA mainly through cluster-mediated indirect effect in aqueous solution

  Chung, W. J., Cui, Y., Huang, F. Y. J., Tu, T. H., Yang, T. S., Lo, J. M., Chiang, C. S. & Hsu, I. C., Sept 22 2014, In: PLoS One. 9, 9, e108162.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• ^99mTc-TRODAT-1 SPECT in healthy and 6-OHDA lesioned parkinsonian monkeys: Comparison with ¹⁸F-FDOPA PET

  Huang, W. S., Ma, K. H., Chou, Y. H., Chen, C. Y., Liu, R. S. & Liu, J. C., Jan 2003, In: Nuclear Medicine Communications. 24, 1, p. 77-83 7 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• ^99mTc-TRODAT-1 SPECT Revealed That Striatal Dopamine Transport Availability Significantly Decreases in Late Mid-Aged Healthy Taiwanese and Then Remains Stable

  Yeh, S. H. H., Tsai, C. J., Yu, T. H., Chiang, Y. H., Lin, S. Z., Peng, N. J. & Huang, W. S., Mar 1 2022, In: Clinical Nuclear Medicine. 47, 3, p. 201-208 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• 9-Anthracenecarboxamide fluorescent probes for selective discrimination of picric acid from mono- and di-nitrophenols in ethanol

  Pandith, A., Kumar, A., Lee, J. Y. & Kim, H. S., Dec 23 2015, In: Tetrahedron Letters. 56, 51, p. 7094-7099 6 p.

  Research output: Contribution to journal › Article › peer-review
  33 Citations (Scopus)

• 9-cis retinoic acid induces neurorepair in stroke brain

  Yu, S. J., Airavaara, M., Wu, K. J., Harvey, B. K., Liu, H. S., Yang, Y., Zacharek, A., Chen, J. & Wang, Y., Dec 1 2017, In: Scientific Reports. 7, 1, 4512.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• 9-cis retinoic acid induces retinoid X receptor localized to the mitochondria for mediation of mitochondrial transcription

  Lin, Y. W., Lien, L. M., Yeh, T. S., Wu, H. M., Liu, Y. L. & Hsieh, R. H., Dec 12 2008, In: Biochemical and Biophysical Research Communications. 377, 2, p. 351-354 4 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• 9-Cis-retinoic acid reduces ischemic brain injury in rodents via bone morphogenetic protein

  Shen, H., Luo, Y., Kuo, C. C., Deng, X., Fang, C. F., Harvey, B. K., Hoffer, B. J. & Wang, Y., Feb 1 2009, In: Journal of Neuroscience Research. 87, 2, p. 545-555 11 p.

  Research output: Contribution to journal › Article › peer-review
  32 Citations (Scopus)

• 9-N-Alkylaminomethylanthracene probes for selective fluorescence sensing of pentafluorophenol

  Pandith, A., Kumar, A. & Kim, H. S., Sept 18 2015, In: RSC Advances. 5, 100, p. 81808-81816 9 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• A 10-item Fugl-Meyer Motor Scale Based on Machine Learning

  Lin, G. H., Huang, C. Y., Lee, S. C., Chen, K. L., Lien, J. J. J., Chen, M. H., Huang, Y. H. & Hsieh, C. L., Apr 1 2021, In: Physical Therapy. 101, 4

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• A 10-year follow-up of triple-negative breast cancer patients in Taiwan

  Lin, C., Chien, S. Y., Kuo, S. J., Chen, L. S., Chen, S. T., Lai, H. W., Chang, T. W. & Chen, D. R., Mar 2012, In: Japanese Journal of Clinical Oncology. 42, 3, p. 161-167 7 p., hyr196.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• A 10-year follow-up study on suicidal mortality after 1999 Taiwan earthquake

  Chen, S. L. S., Lee, C. S., Yen, A. M. F., Chen, H. H., Chan, C. C., Chiu, S. Y. H., Fann, J. C. Y. & Chang, J. C., Aug 1 2016, In: Journal of Psychiatric Research. 79, p. 42-49 8 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• A 10-year retrospective study on mandibular fractures in Northern Taiwan

  Fang, C. Y., Tsai, H. Y., Yong, C. Y., Ohiro, Y., Chang, Y. C. & Teng, N. C., 2023, (Accepted/In press) In: Journal of Dental Sciences.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• A 12-month, prospective, observational study of ranibizumab in treatment-naïve Taiwanese patients with neovascular age-related macular degeneration: the RACER study

  Wu, W-C., Chen, J-T., Tsai, C-Y., Wu, C-L., Cheng, C-K., Shen, Y-D., Tsai, A. & Wu, P-C., Nov 25 2020, In: BMC Ophthalmology. 20, 1, p. 462

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• A 12-year-old boy with an infected ectopic ureter presenting with acute appendicitis-like symptoms and acute scrotum

  Chu, W. Y., Tsao, T. F., Chen, S. L., Chang, H. M., Chen, S. M., Chen, C. Y., Lue, K. H. & Sheu, J. N., Jun 2012, In: Scandinavian Journal of Urology and Nephrology. 46, 3, p. 208-211 4 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• A 17-Year-Old Student with Dysphagia

  Cheng, Y. C., Lou, H. Y., Chang, C-C. & Lin, H-J., 2013, In: Gastroenterological Journal of Taiwan. 30, 1, p. 41-42 2 p.

  Research output: Contribution to journal › Article › peer-review

• A20, ABIN-1/2, and CARD11 mutations and their prognostic value in gastrointestinal diffuse large B-cell lymphoma

  Dong, G., Chanudet, E., Zeng, N., Appert, A., Chen, Y. W., Au, W. Y., Hamoudi, R. A., Watkins, A. J., Ye, H., Liu, H., Gao, Z., Chuang, S. S., Srivastava, G. & Du, M. Q., Mar 15 2011, In: Clinical Cancer Research. 17, 6, p. 1440-1451 12 p.

  Research output: Contribution to journal › Article › peer-review
  59 Citations (Scopus)

• A 20 year clinical and laboratory study of familial b-chronic lymphocytic leukemia in a single kindred

  Caporaso, N. E., Whitehouse, J., Bertin, P., Amos, C., Papadopoulos, N., Muller, J., Whang-peng, J., Tucker, M. A., Fleisher, T. A. & Marti, G. E., Jan 1 1991, In: Leukemia and Lymphoma. 3, 5-6, p. 331-342 12 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• A 22-year-old woman had a lung mass

  Lee, C. H., Cheng, C. J. & Chan, W. P., 2013, In: Annals of the Academy of Medicine Singapore. 42, 2, p. 95-96 2 p.

  Research output: Contribution to journal › Article › peer-review

• A 260- μ W down-conversion demodulator for MICS-band receiver

  Chang, C. H., Gong, C. S. A., Liou, J. C., Tsou, Y. L., Shiu, F. L., Chiou, H. K. & Tu, P. H., Feb 1 2017, In: Journal of Circuits, Systems and Computers. 26, 2, 1750027.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• A 2-year follow-up of swallowing function after radiation therapy in patients with nasopharyngeal carcinoma

  Chang, Y. C., Chen, S. Y., Ting, L. L., Peng, S. S. F., Wang, T. C. & Wang, T. G., Nov 1 2011, In: Archives of Physical Medicine and Rehabilitation. 92, 11, p. 1814-1819 6 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• A 2-Year Longitudinal Relationship Between Work–Family Conflict and Health Among Older Workers: Can Gardening Help?

  Cho, E., Chen, T. Y. & Janke, M. C., Oct 2021, In: Journal of Applied Gerontology. 40, 10, p. 1330-1341 12 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• A 3-day anti-Helicobacter pylori therapy is a good alternative for bleeding peptic ulcer patients with Helicobacter pylori infection

  Hsieh, Y. H., Lin, H. J., Tseng, G. Y., Perng, C. L., Chang, F. Y. & Lee, S. D., 2001, In: Hepato-Gastroenterology. 48, 40, p. 1078-1081 4 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• A 3D model of the membrane protein complex formed by the white spot syndrome virus structural proteins

  Chang, Y. S., Liu, W. J., Lee, C. C., Chou, T. L., Lee, Y. T., Wu, T. S., Huang, J. Y., Huang, W. T., Lee, T. L., Kou, G. H., Wang, A. H. J. & Lo, C. F., 2010, In: PLoS ONE. 5, 5, e10718.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  68 Citations (Scopus)

• A 3-D stackable maskless embedded metal-gate thin-film-transistor nanowire for use in bioelectronic probing

  Chen, M. C., Lin, C. H., Lin, C. Y., Chen, H. C., Lee, T. H., Hua, M. Y., Qiu, J. T., Ho, C. & Yang, F. L., Mar 2014, In: IEEE Transactions on Electron Devices. 61, 3, p. 897-901 5 p., 6740855.

  Research output: Contribution to journal › Article › peer-review

• A 3-year follow-up study on the risk of stroke among patients with conjunctival haemorrhage

  Wang, T. J., Keller, J. J., Sheu, J. J. & Lin, H. C., May 2013, In: Acta Ophthalmologica. 91, 3, p. 226-230 5 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• A 45-kDa ErbB3 secreted by prostate cancer cells promotes bone formation

  Lin, S. H., Cheng, C. J., Lee, Y. C., Ye, X., Tsai, W. W., Kim, J., Pasqualini, R., Arap, W., Navone, N. M., Tu, S. M., Hu, M., Yu-Lee, L. Y. & Logothetis, C. J., Sept 4 2008, In: Oncogene. 27, 39, p. 5195-5203 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  23 Citations (Scopus)

• A 45-year experience of uveal melanoma in Taiwan: Verification of American Joint Committee on Cancer staging system and prognostic factors

  Ma, S. T., Hsieh, Y. T., Wei, Y. H. & Liao, S. L., Jun 2021, In: Journal of the Formosan Medical Association. 120, 6, p. 1361-1368 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Citations (Scopus)

• A 50-year-old man with bilateral pulmonary tumours

  Lin, P. Y., Chen, J. S., Ku, S. C., Wu, M. Z., Yu, C. J. & Yang, P. C., Mar 2008, In: Thorax. 63, 3, p. 193+239

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Citation (Scopus)