5H-8,9-dimethoxy-5-(2-N,N-dimethylaminoethyl)dibenzo[c,h][1,6] naphthyridin-6-ones and related compounds as TOP1-targeting agents: Influence of structure on the ternary cleavable complex formation

John E. Kerrigan, Daniel S. Pilch, Alexander L. Ruchelman, Nai Zhou, Angela Liu, Leroy Liu, Edmond J. LaVoie

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Biochemistry, Genetics and Molecular Biology

Chemistry