Abstract
A 35-year-old man with refractory cutaneous Ki-1 lymphoma was salvaged successfully with oral 13-cis-retinoic acid (1 mg/kg/day). He had a complete remission lasting for 20 months before a single nodule recurred on his skin. Excisional biopsy of the recurrent tumor revealed a distinct morphologic change, suggesting cellular differentiation toward a more benign phenotype. No significant side effects were noted except mild xerostomia, bone pain, and hyperlipidemia. The authors believe that 13-cis-retinoic acid should be considered in the treatment of cutaneous Ki-1 lymphoma.
Original language | English |
---|---|
Pages (from-to) | 2490-2494 |
Number of pages | 5 |
Journal | Cancer |
Volume | 67 |
Issue number | 10 |
Publication status | Published - 1991 |
Externally published | Yes |
ASJC Scopus subject areas
- Cancer Research
- Oncology