髖部骨折與腦中風相關風險之研究

Hip fractures after stroke are frequent; our goal was to estimate the risk of hip fractures after stroke. We used a case control study and analyzed 2007 data from the Taiwan National Health Insurance Research Database. Cases of hip fractures were identified according to the International Classification of Diseases, Ninth Edition, Clinical Modification. A total of 877 hip fractures and 4,385 nonhip fractures after stroke existed in the sampled data. Variables including gender, age, medications (i.e., thiazide diuretics, beta-blockers, calcium channel blockers, nitrates, antidiabetics, antiarrhythmics, bisphosphonates, hormones, and corticosteroids) were controlled for. Data were analyzed using descriptive statistics and logistic regression. The results indicated an increased risk of a hip fracture in patients who experienced a stroke at any time before the index date. Fracture risk was highest among patients who had experienced an ischemic stroke, female patients, and patients aged 71-80 years. This study determined that stroke is associated with a 1.35-fold increase in the risk of a hip fracture. Bone mineral density measurements, fall prevention programs, sunlight exposure, poststroke walking, and increased calcium intake may be necessary to reduce the occurrence of a hip fractures during and after stroke.