補充綠藻萃取物對於運動員脫水後運動疲勞之影響

The purpose of this study was to investigate the effects of acute Chlorella extract supplementation on endurance performance and fatigue markers after dehydration. In this randomized, double-blind crossover study design, 10 participants were divided into Placebo or Chlorella groups. Dehydration (3% body weight) in all subjects was induced by treadmill walking in a high temperature (35°C) and humidity (70%) environment. Subjects were then rehydrated with fluid (6% carbohydrate and 0.04% salt) equal to 1.5 times weight lost. One hundred and thirty ml of Chlorella extract or placebo were administered to the subjects of Placebo or Chlorella groups at the same time according to their groups. Maximal oxygen uptake (VO_(2max)) and markers of oxidative stress, inflammation and anabolism/catabolism were determined before and after dehydration. The results showed that VO_(2max) and exercise time to fatigue were significantly decreased after dehydration in Placebo group. However, VO_(2max), and exercise time to fatigue of Chlorella group were significantly higher than those of Placebo group after dehydration. Dehydration increased levels of white blood cells (WBC), neutrophils, interleukin-6 (IL-6), interleukin-10 (IL-10), thiobarbituric acid reactive substances (TBARS), and superoxide dismutase (SOD). The TBARS level in Chlorella group was significantly lower after dehydration than that in Pl acebo group. Furthermore, testosterone and cortisol levels were significantly increased in Placebo group after dehydration. The cortisol level of Chlorella group was significantly lower 2 hours after dehydration than that of Placebo group. In conclusion, decreased endurance performance and increased oxidative damage and catabolic response after dehydration could be mitigated by acute Chlorella supplementation.