肺癌病患化療期間接受蜂膠照護措施對改善口腔狀態之成效探討

The purpose of this study was to determine the effects of oral care intervention on the incidence of mucositis and dental plaque in lung cancer patients receiving chemotherapy. An experimental design was conducted in this study and 61 patients were randomly assigned to a treatment group (n=30) or control group (n=31). All patients receiving standard protocol of oral care included (1) 90 seconds tooth brush after breakfast and before bed, (2) dental floss use after tooth brush, and (3) 2 times daily rinsing. The major difference between control group and treatment group was 2 times daily rinsing with sterile water and propolis, respectively. The World Health Organization (WHO) mucositis grading system and Oral Assessment Guide (OAG) were used to assess oral status every day during hospitalization and 14 days after chemotherapy. A statistical difference was not found between 2 groups measured by WHO scales. However, OAG score was significantly lower in treatment group (p ＜ 0.001). Plaque significantly reduced in the treatment group (p = 0.002). The result supports the application of propolis oral intervention an effective method for improving mucositis in lung cancer patients receiving chemotherapy.