特級初榨橄欖油與婦科相關疾病之探討

Globally, approximately 20% of women suffer from gynecological disorders, including gynecological cancers, premenstrual syndrome, and conditions arising after menopause. These conditions are often associated with cell proliferation, oxidative stress, and inflammatory responses. Previous research has highlighted the efficacy of the Mediterranean diet in reducing metabolic syndrome and inflammation. The higher consumption of extra virgin olive oil (EVOO) in the Mediterranean diet, obtained through a lower-temperature pressing process that retains valuable polyphenols, including hydroxytyrosol, oleuropein, oleocanthal, and oleacein, has been shown to exhibit significant anti-cancer, anti-inflammatory, and anti-aging effects. Through a literature review, this study finds that the active components of EVOO have therapeutic potential for gynecological cancers, menstrual pain, metabolic syndrome, and osteoporosis after menopause. These components may mitigate symptoms related to gynecological disorders by reducing inflammation and oxidative stress in uterine and bone cells. EVOO supplementation also shows promise as an adjunct therapy for gynecological cancers, potentially reducing tumor size, cancer risk, and enhancing sensitivity to chemotherapy drugs. In conclusion, the abundant polyphenols in EVOO suggest its potential as a nutritional intervention for the prevention and management of gynecological disorders and cancer progression. Recommending moderate consumption of olive oil may help alleviate discomfort during menstruation and mitigate risks associated with post-menopausal metabolic disorders. Although scientific confirmation of EVOO's effectiveness in cancer treatment is currently lacking, its ability to induce oxidative stress in cancer cells, leading to apoptosis and cell cycle arrest, implies its potential in cancer adjuvant therapy. Further rigorous clinical research is warranted to validate its anticancer efficacy.