比較半劑量與正常劑量對比劑在頸部磁振血管造影之初步評估

To evaluate MR angiography (MRA) of the neck using the Time Resolved Imaging of Contrast Kinetics (TRICKS) technique and injection of half-dose gadobenate dimeglumine (Gd-BOPTA) if there is any significant impact on image quality. During the period from March 1, 2013 to October 31, 2013, 40 patients received MRA of the neck with half-dose contrast medium due to the patients glomerular filtration rate between 31 and 60, and they were therefore enrolled into our study. For the control, we randomly selected 40 patients who had MRA with normal-dose contrast medium during the same period. The two groups were compared with respect to vascular contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR). Two radiologists compared the image quality of the two groups in a double-blind setting. All 40 MRAs in the normal-dose group had good image quality. One in 40 MRAs in the half-dose group had suboptimal contrast enhancement, but still allowed image interpretation. Two observers, unaware of the circumstances, deemed no significant differences in image quality between the two groups of patients. The blood vessels of patients injected with normal-dose contrast had higher SNR and CNR than those injected with half-dose. TRICKS MRA of the neck with half-dose contrast did not significantly lower MRA image quality and interpretability. For patients with poor renal function, MRA performed with a reduced contrast dose may decrease the incidence of nephrogenic systemic fibrosis or nephrogenic fibrosing dermopathy.