抗癌危害性藥品給藥防護作業指引

Several studies have documented potential exposure to antineoplastic drugs can occur in many areas of the hospital settings. Precautions should be taken to eliminate or reduce exposure as much as possible for the health care workers who are exposed to these antineoplastic hazardous agents. This guideline was developed through multidisciplinary collaboration with inputs from physicians, nurses, pharmacists, safety and environmental experts, and doctors of occupational health. This guideline is not only based on the best available evidence and expert opinion of professionals, but also the consensus of many guideline users from various health care institutions. This guideline includes thirteen sections: 1) the definition and list of hazardous drugs; 2) the risks of hazardous drug exposure; 3) engineering control and personal protective equipment; 4) the closed system transfer devices; 5) drug procurement, storage, reception and transmission; 6) drug compounding; 7) drug administration; 8) waste management; 9) spill management; 10) continuous quality monitoring; 11) staff training and education; 12) home chemotherapy; 13) medical surveillance. In addition, recommendations for the preparation of oral antineoplastic agents for patients with enteral feeding are provided as appendix. After all, this evidence-based consensus guideline is intended to facilitate the standardization of institutional procedures for the safe handling of antineoplastic hazardous drugs in Taiwanese hospitals. Following these standard procedures will assist in minimizing unnecessary exposure and maximizing safety.