停經後婦女代謝症候群預測因子之探討

The purposes of the study were to explore the metabolic syndrome (MS) risk predictors among adiponectin, insulin resistance, and total cholesterol to high density lipoprotein cholesterol (TC/HDL-C) ratio in postmenopausal women. Seventy-eight postmenopausal women completed this cross-section study in the cardiovascular department of a medical hospital center and community. Data of demography, body compositions and blood sampling were analyzed by chi-squared test, independent t-test, Pearson's correlation, logistic and multiple regression analysis. The postmenopausal women (mean age: 56.91± 6.23 years) in our study had overweight, central obesity (mean waist circumference: 90.09 ± 9.39 cm), higher fasting glucose levels (mean: 104.87±13.56 mg/dL), and declined adiponectin levels (mean: 11.84 ± 6.52 μg/ml). Age, adiponectin, insulin resistance, and TC/HDL-C ratio were significantly predicted MS in postmenopausal women (all p＜0.01, R2=0.52). Results of our study supported the important roles of insulin resistance and adiponectin values in the development of MS, in addition to the components described by the National Cholesterol Education Program Adult Treatment Panel III (2001). Our study results are provided to the key instruments of healthy check-up and primary interventions to improve the health in postmenopausal women.