以多層螺旋電腦斷層之多層面數位重建研究正常呼吸狀態下的聲帶

BACKGROUND: 2D Multi-planar reformatting (2D MPR) is a post-processing technique that is able to create new images from a stack of images in planes other than that of the original stack. We describe here the first use of this method to study normal adult vocal folds during tidal respiration. It is expected that this study will help the study of glottic anatomy and physiology.METHODS: METHODS: A total of 220 adult patients (≥ 18 years old) (122 men and 98 women) aged 45.7 ± 19.1 (average ± SD) were enrolled. These individuals had received cervical spinal computed tomography, but had no disease diagnosed. The image datasets were then transferred to a post-processing computer workstation that allows the generation of 2D MPR. We tried to generate an axial cut at the vocal points of the bilateral arytenoid cartilages and the posterior end of anterior commissure. The thickness of anterior commissure, the straight lengths of the bilateral membranous vocal folds, the included angle of the bilateral membranous vocal folds and glottic airway area were measured. The results were statistically analyzed using two-tail t-tests (α =0.05).RESULTS: The thickness of anterior commissure was greater in men (3.08 ± 1.59 mm) than in women (2.50 ± 1.37 mm) (p = 0.004). The average straight length of bilateral membranous vocal folds was also greater in men (15.39 ± 2.46 mm) than in women (12.13 ± 2.33 mm) (p = 3.79 × 10^(-20)), but the included angle of the bilateral membranous vocal folds was greater in women (42.90 ± 10.97°) than in men (38.89 ± 10.13°) (p = 0.006). The glottic airway area was larger in men (165.79 ± 48.87 mm^2) than in women (107.02 ± 35.18 mm^2) (p = 1.61 × 10^(-20)).CONCLUSIONS: We performed a preliminary study to confirm that the anatomy of the anterior commissure, bilateral membranous vocal folds and glottic airway are different between normal adult men and women during tidal respiration. In addition, age progression may also influence the anatomy of normal adult vocal folds.