以動物實驗探討經陽極表面處理微型骨釘之施力時機與穩固度評估

[Objective] The porous oxide surface characterier of tianium alloy can be improved by the technology of anodization which benefits cell adhesion and tissue growth. It also accelerates the quality and quantity of bone growth that n terms helps to shorten the period of bone healing. The purpose of this study was to evaluate the effects of anodized mini-screws on the stability n vivo. [Materials and Methods] The chosen sizes of the mini-screws were 1.3mm. We used 12 each on three male beagle dogs. We selected edentulous areas for implantation and the time of healing before applying force were 0 week, 2 weeks, and 6 weeks respectively. Then we connected NiTi coil springs to the mini-screws n the same group and the magnitude of force was controlled at 200g. The histology was examined to measure bone-implant contact (BIC). [Results and Discussion] The results showed that the success rates were 87.5%. BIC of the former group were 37.57% (healing time 0 week), 78.52% healing time 2 weeks), and 47.73% (healing time 6 weeks) respectively. These were all higher than previous studies. [Conclusion] In the future development, we are hoping to combine this technology of anodization to shorten the length of mini-screws for clinical use in order to improve their safety and stability.