Translational Approach to Target Csc-Educated Immune Microenvironment in Overcoming Checkpoint Inhibitor Resistance in Head and Neck Cancer

Project: A - Government Institution › b - National Science and Technology Council

Project Details

Description

這項研究探討頭頸部鱗狀細胞癌中腫瘤免疫微環境(TIME)的角色，著重於一個特定的基因網絡（TCT）以及褐藻糖膠為基礎的治療重新編輯TIME和克服免疫檢查點抑制劑抵抗性的潛力。另外, 本計畫探討癌幹細胞透過TCT網路和免疫抑制細胞在腫瘤生成和治療反應中的關鍵影響。
StatusFinished
Effective start/end date8/1/24 → 8/1/24

Keywords

  • Head and Neck Squamous Cell Carcinoma (HNSCC)
  • Tumor Immune Microenvironment (TIME)
  • Immune Checkpoint Inhibitors (ICIs)
  • Cancer Stem Cells (CSCs)
  • TCT oncogenic network
  • Fucoidan-based therapy

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