To Investigate the Role of Usp24 Inhibitor Targeting Ferroptosis as a Potential Therapeutic Approach for Therapy-Resistant Cancers and Fibrosis

Project: A - Government Institutionb - National Science and Technology Council

Project Details

Description

多重抗藥性癌症是個難解的議題,我們想透過脂質代謝去了解正常細胞與癌細胞的差別,並嘗試利用新穎小分子抑制劑(鐵死亡誘導劑)來解決癌症與纖維化疾病。
StatusFinished
Effective start/end date8/1/237/31/24

Keywords

  • drug-resistant cancer
  • fibrosis
  • USP24 small molecualr inhibitor
  • ferroptosis
  • ABC transporter
  • antioxidants
  • lipid ROS