The Association between the Oxidative Stress Markers Urinary 8-Iso-Prostaglandin F2α, 2,3-Dinor-8-Iso-Prostaglandin F2α and 8-Hydroxydeoxyguanine Concentrations, and Levels of Total Urinary Arsenic and Blood Cadmium and Lead, and Chronic Kidney Disease

  • Hsueh, Yu-Mei (PI)

Project: A - Government Institution › b - National Science and Technology Council

Project Details

Description

預期能評估總尿液砷與血鉛和鎘濃度是否藉由此氧化壓力標記-尿液8-iso-PGF2α、2,3-dinor-8-iso-PGF2α 和8-OHdG濃度中介而與慢性腎臟病有關。瞭解尿液8-iso-PGF2α、2,3-dinor-8-iso-PGF2α 和8-OHdG濃度、總尿液砷和血鉛與鎘濃度對慢性腎臟病的相關性與交互作用。此研究結果將有助於預防環境汙染物砷、鉛與鎘的暴露和瞭解尿液8-iso-PGF2α、2,3-dinor-8-iso-PGF2α 和8-OHdG濃度與慢性腎臟病發生的關係，來減緩慢性腎臟病的發生與惡化。
StatusFinished
Effective start/end date8/1/23 → 7/31/24

Keywords

  • 8-iso-prostaglandin F2α
  • 2,3-dinor-8-prostaglandin F2α
  • 8-hydroxydeoxyguanine
  • Total urinary arsenic
  • Blood cadmium
  • Blood lead
  • Chronic kidney disease