Targeting the Btk-Itk Axis as a Potential Therapeutic Strategy for Overcoming Drug Resistance and Inhibiting Brain Metastasis in Lung Cancer

Project: A - Government Institutionb - National Science and Technology Council

Project Details

Description

我們希望透過這個計畫的執行,找到控制肺癌治療之抗藥性的有效方法並以此基礎來治療肺癌的腦轉移,如此將可有效延長晚期肺癌患者的存活,除了對肺癌的學術研究有重大影響外,也可降低肺癌這個十大癌症死因之首的疾病對社會產生的重大負擔;若能因此設計開發出新的藥物,更將對生技產業及國內經濟產生重大貢獻。
StatusFinished
Effective start/end date8/1/217/31/22

Keywords

  • Bruton’s tyrosine kinase (BTK)
  • drug resistant lung cancer
  • BTK inhibitors
  • apoptosis
  • brain metastasis