Synthesis and Clinical Investigations of Novel Bismuth (Or Zirconium) Hafnium Oxide for Dental Filling and Radiopacifying Application

Project: A - Government Institutionb - National Science and Technology Council

Project Details


Bismuth oxide is a rare-earth metal oxide with the melting point at 824 oC. There are various polymorphic materials of bismuth oxide that can be used as the solid electrolyte and photo catalyst. Additionally, bismuth oxide is also a major constitute of mineral trioxide aggregate (MTA) and serves as the radio pacifier within MTA. The R&D trends of MTA mainly focus on its constitution, biocompatibility, physical and chemical properties, and its solidification properties, etc.. In the present proposal, we will develop bismuth/hafnium and zirconium/hafnium oxide composite powder to be used as the dental filling and radiopacifying materials. In the first year, various processing techniques including mechanical milling, sol-gel process, co-precipitation, and spray pyrolysis will be used to prepare desired composite powder and followed by post heat treatment. Material characterization of these composite powder will be performed. The composite powder will be used to prepare mineral trioxide aggregates (75% Portland cement, 25% rediopacifying material, and 5% other material). The setting time, mechanical properties and radiopacity of solidified MTAs will be examined. In the second year, optimized technique with suitable processing parameters will be determined. The constitution of MTA will be adjusted and different solutions will be attempted to further improve the clinical use of composite powder. Biocompatibility and animal test of the optimum composition will be performed and confirmed in its practical application.
Effective start/end date8/1/167/31/17


  • bismuth oxide
  • zirconium oxide
  • hafnium oxide
  • composite powder
  • mineral trioxide aggregates
  • mechanical milling
  • sol-gel
  • co-precipitation
  • spray pyrolysis
  • dental material
  • solidification
  • radiopacity


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