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Studying the Role of Inflammatory Macrophages in the Recovery Process from Hydroureteronephrosis and Applying in Identifying Potential Manipulating Strategies

Project: A - Government Institutionb - National Science and Technology Council

Project Details

Description

此研究在評估藉由調控巨噬細胞的脂質代謝對於臨床常見的輸尿管積水性腎病變的回復過程中的影響,利用適切的動物模式,預期可以針對其進行調控所造成的影響進行評估。如對於此類疾病患者之處置後病情控制情形能有所提升,預期可以降低後續形成慢性腎臟病的情形,達到對社會、經濟與學術各面向之諸多影響。
StatusFinished
Effective start/end date8/1/257/31/26

Keywords

  • Hydroureteronephrosis
  • Myofibroblast
  • Macrophage polarization macrophage-to-myofibroblast transition
  • Peroxisome proliferator-activated receptor gamma