Study on the Immunopathological Role of Macrophage Migration Inhibitory Factor in Pulmonary Fibrosis

Project: A - Government Institution › b - National Science and Technology Council

Project Details

Description

隨著環境變遷人口老化，肺纖維化疾病日趨嚴重卻面臨治療的侷限。因此，對於新穎藥物與治療開發是為迫切需要。本計畫以新的免疫面向與轉錄組體學探究肺部纖維化成因，針對在慢性肺部疾病具有重要角色的巨噬細胞移動抑制因子(MIF)進行研究。藉由系統性探究MIF於疾病進程與免疫傾斜間的調節，進以尋求新穎用藥把點與有效治療策略。
StatusFinished
Effective start/end date8/1/21 → 7/31/22

Keywords

  • Pulmonary fibrosis
  • MIF
  • Fibrocyte
  • Type 2 immune response
  • Combination therapy

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