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Multi-Functional Enzyme Dual-Crosslinked Alginate-Tyramine-Platelet-Rich Plasma for Meniscus Repair

Project: A - Government Institutionb - National Science and Technology Council

Project Details

Layman's description

半月板缺損治療面臨挑戰,如自然癒合難、缺標準方法,雖用PRP治療,但存在問題,如PRP分解快、效果差,需改進。本研究旨在開發ALG-TYR/TYRase/CaO2水凝膠作為PRP載體,提高PRP的生體可利用性,並在體外和體內實驗中驗證其效果。該方法有望改善半月板修復,對軟骨修復、組織再生等領域具有應用價值。
StatusFinished
Effective start/end date3/1/242/28/25

Keywords

  • Meniscal deficiency
  • hydrogel
  • high-concentration platelet-rich plasma (PRP)
  • tissue engineering
  • biomaterials